PMID: 42323Jul 1, 1979

Adverse reactions following fazadinium-thiopentone induction

J P Alexander


Three cases of hypersensitivity to an anaesthetic induction with fazadinium and thiopentone are described. One reaction was fatal. Two patients had documented and the third presumptive previous exposure to thiopentone, and all had a history of allergy (skin rash) to penicillin. None of the patients had received fazadinium before. The possibility that fazadinium contributed to the severity of the reactions is conjectural.


Jul 8, 2000·Paediatric Anaesthesia·G BriassoulisA Alikatora
Jun 1, 1982·Anaesthesia·M S Alam


Mar 1, 1978·British Journal of Anaesthesia·D E Rowlands, K Fidler
May 1, 1975·British Journal of Anaesthesia·R S ClarkeJ A Sutton
Feb 1, 1976·British Journal of Anaesthesia·J W Dundee
Apr 1, 1978·Anaesthesia·B Walton
Dec 3, 1977·British Medical Journal·H J Lewi, T V Taylor
Sep 1, 1976·British Journal of Anaesthesia·J WatkinsA Padfield
Sep 17, 1977·British Medical Journal·J M Evans, J A Keogh
Sep 1, 1977·Anaesthesia·M M Fischer
Oct 22, 1977·British Medical Journal·J WatkinsN Appleyard
May 1, 1976·Canadian Anaesthetists' Society Journal·D C Chung
Nov 1, 1976·British Journal of Anaesthesia·J WatkinsR S Clarke
May 1, 1976·British Journal of Anaesthesia·J WatkinsJ A Thornton
Jan 12, 1974·British Medical Journal·J W DundeeD Grainger
Apr 1, 1974·British Journal of Anaesthesia·H S YoungJ W Dundee
Aug 1, 1972·Anaesthesia and Intensive Care·I P Unsworth
Jul 1, 1971·Anaesthesia·R P HolmesE R Williams
Oct 1, 1971·Anaesthesia·W Sniper
Jun 11, 1966·British Medical Journal·T T CurrieJ S Peters
Apr 1, 1967·Anaesthesia·L E Carrie, R L Buchanan

Related Concepts

Immediate Hypersensitivity
Bronchial Spasm
Anesthesia, Intravenous
Hemolytic Complement
Immunoglobulin E

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