PMID: 42471Nov 10, 1979

Adverse reactions to drugs in general practice

British Medical Journal
C R Martys


Of 817 patients in a general-practice survey of adverse reactions to drugs, 41% were thought to have "certainly" or "probably" had a reaction to the drug prescribed. Adverse effects on the gastrointestinal and central nervous systems were the most frequently reported, and 90% of reactions had occurred by the fourth day of treatment. More patients given drugs acting on the central nervous system and antihistamines reported reactions than those in other categories. A higher incidence of adverse drug effects is shown in this general-practice survey than in other, mainly hospital-based, surveys. Further intensive surveillance for adverse effects of drugs is recommended to provide additional information on the burden of drug-induced disease in the community.


Jun 18, 1977·British Medical Journal·D C SkeggJ Perry
Mar 6, 1976·British Medical Journal·R Law, C Chalmers
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Related Concepts

Central Nervous System Agents
CNS Disorder
Family Medicine (Field)
Cholera Infantum
Antihistamines, Classical

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