PMID: 42471Nov 10, 1979

Adverse reactions to drugs in general practice

British Medical Journal
C R Martys

Abstract

Of 817 patients in a general-practice survey of adverse reactions to drugs, 41% were thought to have "certainly" or "probably" had a reaction to the drug prescribed. Adverse effects on the gastrointestinal and central nervous systems were the most frequently reported, and 90% of reactions had occurred by the fourth day of treatment. More patients given drugs acting on the central nervous system and antihistamines reported reactions than those in other categories. A higher incidence of adverse drug effects is shown in this general-practice survey than in other, mainly hospital-based, surveys. Further intensive surveillance for adverse effects of drugs is recommended to provide additional information on the burden of drug-induced disease in the community.

References

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Citations

Apr 5, 2002·Computer Methods and Programs in Biomedicine·Abdallah M Mangoud, Faleh A Al-Ruwashed
Mar 11, 2003·Critical Care Medicine·Emilio VargasFernando Hernando
Jun 1, 1993·British Journal of Clinical Pharmacology·T P De Vries
Mar 21, 1981·British Medical Journal·C R Martys
Oct 14, 1995·BMJ : British Medical Journal·A W AsscherV B Whitmarsh
Feb 1, 1993·The American Review of Respiratory Disease·H Milgrom, B G Bender
Mar 10, 2012·PloS One·Rebecca Mary Diane SmythPaula Williamson
Apr 26, 2001·Journal of the American Medical Informatics Association : JAMIA·B HonigmanD W Bates
Jul 26, 2002·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Michel Aubé
Jan 1, 1994·Journal of Clinical Pharmacology·A G Recchia, N H Shear
May 13, 2008·Journal of Clinical Epidemiology·Charles E LeonardJoshua P Metlay
Dec 1, 1980·Social Science & Medicine. Medical Psychology & Medical Sociology·A Melville
Nov 1, 1982·Journal of the American Geriatrics Society·P P Lamy
Feb 1, 1988·Journal of the American Geriatrics Society·L Nolan, K O'Malley
Feb 1, 1985·The Journal of Pediatrics·M S KramerD G Leduc
Aug 2, 2007·The Annals of Pharmacotherapy·Linda Aagaard ThomsenArne Melander

Related Concepts

Central Nervous System Agents
CNS Disorder
Family Medicine (Field)
Cholera Infantum
Antihistamines, Classical

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