Adverse reactions to patent blue V dye - The NEW START and ALMANAC experience

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
L BarthelmesNEW START and ALMANAC study groups

Abstract

Blue dye with or without isotope has been widely used to identify the sentinel lymph node(s) in breast cancer. Patent blue V is used in the UK while its isomer isosulfan blue is used in the US. The allergic potential of isosulfan blue is well documented (1.4% adverse reactions) but that of patent blue V is less clearly defined. In this paper we review the adverse reactions of patent blue V in 7,917 patients who participated in the NEW START training programme and the ALMANAC trial. All patients underwent sentinel lymph node biopsy for breast carcinoma using patent blue V in combination with (99m)Tc-albumin colloid. In total, 72 of 7,917 (0.9%) patients experienced adverse reactions : non-allergic reactions were observed in 4 (0.05%) patients, 23 (0.3%) patients had minor grade I allergic skin reactions (urticaria, blue hives, pruritus, or generalised rash) and 16 (0.2%) had grade II reactions (transient hypotension/bronchospasm/laryngospasm). Severe Grade III reactions (severe hypotension requiring vasopressor support and/or change/abandoning of planned procedure and/or HDU/ITU admission) were noted in 5 (0.06%) patients. The type of adverse reaction was not specified in 24 (0.3%) patients. No mortality was recorded. The allerg...Continue Reading

References

Sep 16, 1999·Annales Françaises D'anesthèsie Et De Rèanimation·M C Laxenaire
Jul 30, 2002·Anesthesia and Analgesia·Leslie L MontgomeryPatrick I Borgen
Oct 18, 2002·American Journal of Surgery·Walter D BlessingGeorge M Fuhrman
Apr 5, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·P RzymskiS Sajdak
May 20, 2004·The British Journal of Dermatology·S WöhrlM Binder
Aug 3, 2004·International Seminars in Surgical Oncology : ISSO·Gurpreet Singh-Ranger, Kefah Mokbel
Sep 18, 2004·Journal of Clinical Anesthesia·M Denise DaleyHenry M Kuerer
Nov 18, 2004·Archives of Surgery·Antonio PiñeroPascual Parilla
Jan 14, 2005·The Breast Journal·Ian K KomenakaMahmoud B El-Tamer
Jun 25, 2005·Anesthesia and Analgesia·Pascale DewachterPaul Michel Mertes
May 3, 2006·Contact Dermatitis·Kathrin SchererVerena Figueiredo
Sep 9, 2006·The Breast Journal·Mehra Golshan, Faina Nakhlis
Jan 12, 2008·The Breast Journal·Philip VargheseRobert Carpenter

❮ Previous
Next ❯

Citations

Mar 13, 2010·Der Anaesthesist·V RoglerJ Reutershan
Dec 1, 2009·The Indian Journal of Surgery·Amit Goyal
Mar 26, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Reita H NybergJohanna Mäenpää
Feb 22, 2012·Asia Pacific Allergy·Ania L MansonSuranjith L Seneviratne
Jan 18, 2013·Indian Journal of Anaesthesia·Swagata Tripathy, Priya V Nair
Jul 16, 2014·Immunology and Allergy Clinics of North America·Knut Brockow, Mario Sánchez-Borges
Aug 21, 2013·Breast Cancer Research and Treatment·Bauke AnningaMichael Douek
Feb 21, 2016·Annals of Surgical Oncology·Bauke AnningaUNKNOWN MELAMAG Multicentre Trialists Group
Apr 15, 2014·Journal of Pediatric Surgery·Ciro EspositoAlessandro Settimi
Nov 7, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Marianna LucováZuzana Klimová
Jan 5, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·V WhiteM Carr
Sep 16, 2015·Annales de dermatologie et de vénéréologie·A HamelinS Barete
Dec 14, 2011·Anaesthesia·N QuineyM Kissin
Feb 28, 2013·The Journal of Dermatology·Nao KusutaniMasamitsu Ishii
Dec 12, 2012·Acta Anaesthesiologica Scandinavica·O BrenetJ-M Malinovsky
Feb 11, 2012·Anaesthesia·A HegartyS O Riain
Aug 13, 2011·Anaesthesia·L Robinson
Sep 28, 2012·ANZ Journal of Surgery·April WongUNKNOWN Breast Surgeons of Australia and New Zealand Incorporated (BreastSurgANZ)
Jun 26, 2010·The Breast : Official Journal of the European Society of Mastology·L BarthelmesR E Mansel
Jan 22, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S M SchmidU Güth
Jan 30, 2015·The British Journal of Surgery·B AnningaM Douek
Jun 7, 2015·Gynecologic Oncology·Beatrice CormierUNKNOWN Communities of Practice (CoP) Group of Society of Gynecologic Oncology of Canada (GOC)
Feb 16, 2015·The Breast : Official Journal of the European Society of Mastology·Susan PrendevilleMichael W Bennett
Feb 4, 2014·The Breast : Official Journal of the European Society of Mastology·Marc ThillNik Hauser
Jul 23, 2016·Annals of Surgical Oncology·J Michael Dixon
Oct 18, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Anabela RochaNicolas Bourdel
Jan 28, 2017·Journal of Controlled Release : Official Journal of the Controlled Release Society·Ernest A AzzopardiIain S Whitaker
Dec 10, 2015·Acta Cirúrgica Brasileira·Paulo Henrique Diógenes VasquesLuiz Gonzaga Porto Pinheiro
Jun 18, 2017·Nanomedicine·Muneer AhmedMichael Douek
Dec 5, 2017·Current Breast Cancer Reports·Nisha Sharma, Karina Cox
Sep 3, 2010·The British Journal of Surgery·D M LayfieldR I Cutress
Sep 28, 2013·Expert Review of Clinical Immunology·Allison Worth, Aziz Sheikh
Oct 9, 2015·Clinical Nuclear Medicine·Gianpiero MancaPatrick M Colletti
Jul 7, 2012·Current Opinion in Allergy and Clinical Immunology·Paul M MertesJean M Malinovsky
Oct 2, 2012·Biomedical Optics Express·Franklin TellierPatrick Poulet
Jun 8, 2018·European Journal of Nuclear Medicine and Molecular Imaging·Benedikt Michael SchaarschmidtThorsten Dirk Pöppel
Dec 1, 2018·Breast Care·Amit Goyal
Jan 19, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Lea A MoukarzelMario M Leitao

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

© 2022 Meta ULC. All rights reserved