Advice on drug safety in pregnancy: are there differences between commonly used sources of information?

Drug Safety : an International Journal of Medical Toxicology and Drug Experience
Sofia Kristina Frost Widnes, Jan Schjøtt

Abstract

Safety regarding use in pregnancy is not established for many drugs. Inconsistencies between sources providing drug information can give rise to confusion with possible therapeutic consequences. Therefore, it is important to measure clinically important differences between drug information sources. The objective of this study was to compare two easily accessible Norwegian sources providing advice on drug safety in pregnancy - the product monographs in the Felleskatalog (FK), published by the pharmaceutical companies, and the five regional Drug Information Centres (DICs) in Norway - in addition to assessing the frequency of questions regarding drug safety in pregnancy made to the DICs according to the Anatomical Therapeutic Chemical (ATC) classification system. Advice on drug use in pregnancy provided by the DICs in 2003 and 2005 were compared with advice in the product monographs for the respective drugs in the FK. Comparison of advice was based on categorization to one of four categories: can be used, benefit-risk assessment, should not be used, or no available information. A total of 443 drug advice were categorized. Seven out of ten of drugs frequently enquired about, according to the ATC system, were drugs acting on the ner...Continue Reading

References

Jan 1, 1988·European Journal of Clinical Pharmacology·O KasiloG Tognoni

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Citations

Oct 21, 2009·European Journal of Clinical Pharmacology·Hedvig NordengAdrienne Einarson
Oct 6, 2010·Pharmacy World & Science : PWS·Linda A ReppeJan Schjøtt
Mar 1, 2014·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Emma BrownNeil Hotham
Mar 19, 2020·Maternal and Child Health Journal·Kristine Heitmann, Jan Schjøtt
Jul 21, 2010·European Journal of Clinical Pharmacology·Viktorija ErdeljićMatea Radacić-Aumiler
Jan 19, 2016·Journal of Clinical Pharmacy and Therapeutics·J Schjøtt
Feb 3, 2019·Journal of Clinical Pharmacy and Therapeutics·Jan Schjøtt, Olav Spigset
Jun 26, 2012·Birth Defects Research. Part A, Clinical and Molecular Teratology·Rebecca L Hancock-HowardGideon Koren
Dec 5, 2008·European Journal of Clinical Pharmacology·Sofia Kristina Frost Widnes, Jan Schjøtt
May 17, 2012·Archives of Women's Mental Health·Orit Avni-Barron, Renu Gupta
Jun 27, 2015·Acta Obstetricia Et Gynecologica Scandinavica·Ulrika NörbyBirger Winbladh
Sep 27, 2012·European Journal of Clinical Pharmacology·Ulrika NörbyLars L Gustafsson
Sep 17, 2014·British Journal of Clinical Pharmacology·Blanca ArguelloFernando Fernandez-Llimos

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