PMID: 8596716Mar 1, 1996Paper

Aerobic capacity and skeletal muscle properties of normoxic and hypoxic rats in response to training

Pflügers Archiv : European journal of physiology
A AbdelmalkiR Favier

Abstract

The aim of this study was to determine, in the rat, the effects of chronic exposure (7-9 weeks) to normobaric hypoxia (FIO2=0.13, equivalent to 3700 m altitude) on cardiac and skeletal muscle properties, on maximal oxygen uptake (VO2max), and endurance time to exhaustion (ETE). In addition, we evaluated the impact of endurance training (90 min of treadmill running per day, 5 days per week, for 9 weeks) on these parameters. The results were compared to normoxic rats fed ad libitum (NAL) and to normoxic pair-weight (NPW) animals in order to take into account the influence of hypoxia on growth rate. It was found that, in sedentary rats, hypoxia results in stunted growth, adrenal atrophy, a significant reduction of cross-sectional area of fast-twitch (type II) fibres, a reduced capillary-to-fibre ratio (C/F), and a reduced oxidative capacity (decreases in citrate synthase and 3-hydroxy-Acyl CoA dehydrogenase activities) of the plantaris muscle. These effects are mainly related to the anorexic effects of prolonged exposure to hypoxia. Nevertheless, hypoxic (H) rats displayed higher VO2max and ETE values when compared either to NAL or to NPW animals. Endurance training resulted, in all groups (H, NAL, NPW), in a significant change of...Continue Reading

References

Jan 1, 1976·Annual Review of Physiology·J O Holloszy, F W Booth
Oct 1, 1976·The American Journal of Physiology·S E Barrie, P Harris
Nov 1, 1979·The Journal of Physiology·G Goldspink, P S Ward
Sep 16, 1977·Pflügers Archiv : European journal of physiology·A H Sillau, N Banchero
Jul 1, 1991·Journal of Applied Physiology·B SimiR J Favier
Feb 1, 1990·Journal of Applied Physiology·M MizunoB Saltin
Feb 1, 1990·International Journal of Sports Medicine·H HowaldP Cerretelli
Feb 1, 1990·International Journal of Sports Medicine·H HoppelerP Cerretelli
Jan 1, 1990·European Journal of Applied Physiology and Occupational Physiology·K ItohM Itoh
Jun 1, 1990·Journal of Applied Physiology·N TerradosL Kaijser
Jan 1, 1985·The Japanese Journal of Physiology·S TaguchiK Itoh
Dec 1, 1988·Journal of Applied Physiology·M S RoseA Cymerman
Dec 1, 1974·The American Journal of Physiology·A J Gold, L C Costello
Aug 1, 1973·The American Journal of Physiology·L F Cipriano, N Pace
Jan 1, 1972·Calcified Tissue Research·D G Walker
Sep 1, 1972·The Japanese Journal of Surgery·M OgawaT Sugimoto
Dec 1, 1969·Journal of Applied Physiology·H RoskammH Reindell
Sep 1, 1967·The American Journal of Physiology·P K Pattengale, J O Holloszy
Jan 1, 1984·Comparative Biochemistry and Physiology. A, Comparative Physiology·S E TerblancheW Oelofsen
Nov 1, 1984·Proceedings of the Society for Experimental Biology and Medicine·L C Ou, R P Smith
Nov 1, 1984·The American Journal of Anatomy·R B Armstrong, R O Phelps
Apr 1, 1980·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·F J BuickE C Meyers
Jun 1, 1995·Journal of Applied Physiology·R FavierH Hoppeler

❮ Previous
Next ❯

Citations

Apr 5, 2005·Pflügers Archiv : European journal of physiology·Marion FaucherMonique Badier
Sep 5, 2002·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·K A HammondD M Kristan
Nov 3, 2010·Biological Reviews of the Cambridge Philosophical Society·Kristian Gundersen
Feb 25, 2003·The Journal of Physiology·Merete EkmarkKristian Gundersen
Aug 26, 1998·Proceedings of the National Academy of Sciences of the United States of America·G B McClellandJ M Weber
Dec 5, 2014·Extreme Physiology & Medicine·James A Horscroft, Andrew J Murray
May 25, 2007·Respiratory Physiology & Neurobiology·Fabrice Favret, Jean-Paul Richalet
Jul 2, 2015·Journal of Cellular Physiology·Ilse G M SlotHarry R Gosker
Sep 21, 2010·The Journal of Surgical Research·Efstathios V KotidisSpiros T Papavramidis
Jan 16, 2013·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Jianzheng HeQiang Chen
Nov 17, 2004·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Grant B McClelland
May 12, 2004·Respiratory Physiology & Neurobiology·Ewald R WeibelHans Hoppeler
Aug 25, 2015·Cellular and Molecular Life Sciences : CMLS·F B FavierH Benoit
Oct 5, 2007·Wilderness & Environmental Medicine·Usha PanjwaniPratul Kumar Banerjee
Sep 2, 2017·International Journal of Molecular Sciences·Eva L PetersRichard T Jaspers
Mar 31, 2004·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Anne K SwisherRachel Yeater
Jan 13, 2017·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Daphne S LauGrant B McClelland
Oct 21, 2016·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Richard T JaspersPieter de Lange
May 10, 2017·Frontiers in Immunology·Hua SuChun Zhang
Mar 20, 1998·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·O BossJ P Giacobino
Jan 1, 2017·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Richard T JaspersPieter de Lange
Jun 19, 2001·American Journal of Physiology. Heart and Circulatory Physiology·D DeveciS Egginton
Mar 16, 2002·Journal of Applied Physiology·Grant B McClelland, George A Brooks
Jan 18, 2003·Journal of Applied Physiology·Parco M SiuStephen E Alway
Aug 14, 2001·American Journal of Physiology. Endocrinology and Metabolism·G B McClellandJ M Weber
May 12, 2009·American Journal of Physiology. Heart and Circulatory Physiology·R C I WüstH Degens
Jul 27, 2014·Biology Open·Richard T JaspersWillem J van der Laarse

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.