Aerobic capacity in persons with multiple sclerosis: a systematic review and meta-analysis

Sports Medicine
Martin Langeskov-ChristensenUlrik Dalgas

Abstract

Aerobic capacity (VO2max) is a strong health and performance predictor and is regarded as a key physiological measure in the healthy population and in persons with multiple sclerosis (PwMS). However, no studies have tried to synthesize the existing knowledge regarding VO2max in PwMS. The objectives of this study were to (1) systematically review the psychometric properties of the VO2max test; (2) systematically review the literature on VO2max compared with healthy populations; (3) summarize correlates of VO2max; and (4) to review and conduct a meta-analysis of longitudinal exercise studies evaluating training-induced effects on VO2max in PwMS. A systematic literature search of six databases (PubMed, EMBASE, Cochrane Library, PEDro, CINAHL and SPORTDiscus) was performed. To be included, the study had to (1) enrol participants with definite MS according to defined criteria; (2) assess aerobic capacity (VO2max) by means of a graded exercise test to voluntary exhaustion; (3) had undergone peer review; and (4) be available in English, Danish or Dutch. The psychometric properties of the VO2max test in PwMS were reviewed with respect to reliability, validity and responsiveness. Simple Pearson correlation analysis was used to assess th...Continue Reading

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Citations

Feb 21, 2016·Archives of Physical Medicine and Rehabilitation·Matthew E PlattaLara A Pilutti
May 22, 2016·Journal of the Neurological Sciences·Martin Langeskov-ChristensenUlrik Dalgas
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Nov 17, 2017·Neurodegenerative Disease Management·Ulrik Dalgas
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Jul 29, 2016·Multiple Sclerosis : Clinical and Laboratory Research·Peter FeysStine Lykke Andersen
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Nov 25, 2020·Multiple Sclerosis : Clinical and Laboratory Research·Martin Langeskov-ChristensenUlrik Dalgas
Jan 28, 2021·Multiple Sclerosis and Related Disorders·Charly KeytsmanBert O Eijnde
Sep 30, 2021·Physiotherapy Research International : the Journal for Researchers and Clinicians in Physical Therapy·Moira SmithRuth Barker
Oct 9, 2021·Annals of Physical and Rehabilitation Medicine·Sara Reina-GutiérrezAna Torres-Costoso
Dec 3, 2020·Neurology·Martin Langeskov-ChristensenUlrik Dalgas
Jul 2, 2021·International Journal of Sports Medicine·Marit Lea SchlagheckPhilipp Zimmer

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