Aerobic exercise improves measures of vascular health in diabetic peripheral neuropathy

The International Journal of Neuroscience
Sandra A BillingerPatricia M Kluding

Abstract

Aerobic exercise improves vascular endothelial function in people with Type 2 diabetes mellitus (T2DM). There is minimal information available regarding vascular health in people with T2DM and diabetic peripheral neuropathy (DPN). Thus, the primary aim of this secondary analysis was to determine whether a 16-week aerobic exercise intervention could improve vascular health in people with T2DM and DPN. A secondary aim was to explore the relationship between changes in flow-mediated dilation (FMD) and the number of years since diagnosis of DPN. We examined whether a 16-week aerobic exercise intervention would improve vascular health in people with T2DM and DPN. We used Doppler ultrasound to assess brachial artery diameter and peak shear at baseline and post-exercise. Paired t-tests were used to determine whether the outcome measures improved from baseline to post-intervention. Pearson correlation assessed the relationship between DPN (years) and the percent change score (pre- to post-intervention) for FMD. Seventeen individuals were included in the data analysis. After the intervention, peak diameter increased (3.9 (0.5) to 4.0 (0.5) mm; p = 0.07). Time to peak shear occurred at 60.5 (24.6) seconds when compared to baseline at 68....Continue Reading

References

Nov 14, 1997·Arteriosclerosis, Thrombosis, and Vascular Biology·E J MattssonA W Clowes
Nov 24, 1999·Neurology·D R CornblathT Joh
Aug 31, 2001·Journal of the American College of Cardiology·A MaioranaD Green
Jan 15, 2002·Journal of the American College of Cardiology·Mary C CorrettiUNKNOWN International Brachial Artery Reactivity Task Force
Oct 19, 2010·American Journal of Physiology. Heart and Circulatory Physiology·Dick H J ThijssenDaniel J Green
Jun 22, 2012·Journal of Diabetes and Its Complications·Patricia M KludingDouglas E Wright
Nov 1, 2012·Journal of Neurologic Physical Therapy : JNPT·Sandra A BillingerMichael A Rippee
Sep 7, 2014·American Journal of Physiology. Heart and Circulatory Physiology·Christopher J A PughDaniel J Cuthbertson
Sep 28, 2014·European Journal of Applied Physiology·Tim H A SchreuderDick H J Thijssen
Jan 8, 2015·Journal of Exercise Nutrition & Biochemistry·Moon-Hyon Hwang, Sangho Kim
Feb 7, 2015·Arteriosclerosis, Thrombosis, and Vascular Biology·Guillaume WaltherAgnès Vinet

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Citations

Mar 15, 2018·The European Journal of Neuroscience·Rachael S AllenMachelle T Pardue
Mar 11, 2017·Journal of Applied Physiology·Sandra A BillingerDavid C Poole
Jan 10, 2018·Frontiers in Psychology·Ashley N ClausenRobin L Aupperle
Sep 16, 2017·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Jason-Flor V SisanteSandra A Billinger
Jan 10, 2019·Journal of Cellular Physiology·Habib YaribeygiAmirhossein Sahebkar
Jul 1, 2019·Journal of Alzheimer's Disease : JAD·Yumei LiuSandra A Billinger
Oct 27, 2020·Cardiopulmonary Physical Therapy Journal·Sophy J PerdomoSandra A Billinger

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