Feb 13, 2014

Aerobic exercise influences quality of life of children and youngsters with congenital heart disease: a randomized controlled trial

The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine
Karolijn DulferElisabeth M W J Utens


To evaluate effects of an exercise program on health-related quality of life (HRQoL) in children and adolescents with tetralogy of Fallot (ToF) or a Fontan circulation. Stratified, randomized, controlled intervention study conducted in five participating centers of pediatric cardiology in The Netherlands. In total, 93 patients, aged 10-25 years, with surgical repair for tetralogy of Fallot or with a Fontan circulation for single-ventricle physiology were included. They were randomly allocated with a ratio of 2:1 to: (1) a 12-week period with an exercise program for 3 times per week or (2) to a control group. Randomization was stratified by age, gender, and cardiac diagnosis. At baseline and follow-up after 12 weeks, all participants completed Web-based age-appropriate HRQoL questionnaires. Primary analyses involved change in HRQoL during follow-up. Secondary analyses concerned influence of cardiac diagnosis and comparison with normative data. Forty-eight (86%) and 32 (86%) patients in the exercise-group and control-group respectively completed all questionnaires at baseline and follow-up. Compared with the control-group, children, aged 10-15 years, in the exercise-group improved significantly on self-reported cognitive function...Continue Reading

Mentioned in this Paper

Exercise, Isometric
Randomized Controlled Trial (Publication)
Congenital Heart Disease
Physical Symptom
Exercise Tolerance
Harassment, Non-Sexual
Hemi-Fontan Procedure

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