Aerobic physical exercise improved the cognitive function of elderly males but did not modify their blood homocysteine levels

Dementia and Geriatric Cognitive Disorders Extra
Hanna Karen M AntunesVânia D'Almeida

Abstract

Physical exercise influences homocysteine (Hcy) concentrations, cognitive function and the metabolic profile. The purpose of this study was to investigate the influence of regular physical exercise on Hcy levels, the metabolic profile and cognitive function in healthy elderly males before and after an endurance exercise program. Forty-five healthy and sedentary volunteers were randomized into 2 groups: (1) a control group asked not to change their normal everyday activities and not to start any regular physical exercise program and (2) an experimental group trained at a heart rate intensity corresponding to ventilatory threshold 1 (VT-1) for 60 min/day 3 times weekly on alternate days for 6 months using a cycle ergometer. All volunteers underwent cognitive evaluations, blood sample analyses and ergospirometric assessments. A significant improvement in cognitive function was observed in the experimental group compared with the control group (p < 0.05). No significant changes in Hcy levels were observed in the experimental group (p > 0.05), but there was a significant increase in peak oxygen consumption and workload at VT-1 as well as a significant improvement in cholesterol, triglycerides, HDL, glucose, alkaline phosphatase, ure...Continue Reading

Citations

Jan 27, 2016·Physiology & Behavior·Hanna Karen Moreira AntunesMarco Tulio de Mello
Jul 30, 2015·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·H K AntunesO F A Bueno
Nov 22, 2017·Metabolic Syndrome and Related Disorders·Natalie PodolskiChristian Brinkmann
Aug 18, 2017·Therapeutic Advances in Chronic Disease·Gopalkumar RakeshAnthony S Zannas
Mar 18, 2016·PloS One·Rafael DeminiceFernando Tadeu Trevisan Frajacomo
Nov 11, 2018·Current Nutrition Reports·Chen ZhaoNikolaos Scarmeas
Apr 4, 2021·International Journal of Environmental Research and Public Health·Eduardo Vásquez-AranedaIgor Cigarroa

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