Aetiology of diarrhoea and virulence properties of diarrhoeagenic Escherichia coli among patients and healthy subjects in southeast Nigeria.

Journal of Health, Population, and Nutrition
E I Nweze

Abstract

Diarrhoeal diseases are one of the most important causes of illness and death all over the world. In Nigeria, the aetiology of diarrhoeagenic bacteria and the virulence of various Escherichia coli pathotypes have not been well-studied because most currently-published data were from the southwestern axis of the country. In total, 520 stool samples were collected from infants, young children, and other age-groups with acute diarrhoeal diseases in Enugu and Onitsha, southeastern Nigeria. Stool samples were collected from 250 apparently-healthy individuals, with similar age distribution and locality, who were considered control subjects. The stool samples were screened for diarrhea-causing bacterial agents. E. coli strains were isolated from both the groups and were examined by polymerase chain reaction (PCR) for 16 virulence genes. Of the 520 stool samples in the diarrhoea group, 119 (44.74%) were E. coli. Fifty (49.02%) were enteropathogenic E. coli (EPEC), 22 (21.57%) were enterotoxigenic E. coli (ETEC) while 7.84% was enteroaggregative E. coli (EAEC). Sex had no effect on the distribution of diarrhoeagenic bacteria, except for EIEC. The E. coli strains isolated from the diarrhoea and healthy asymptomatic age-matched control gro...Continue Reading

Citations

Jul 9, 2011·The British Journal of Nutrition·Julia B EwaschukCatherine J Field
Nov 14, 2013·PloS One·Xiao ChenLanjuan Li
Oct 16, 2012·Journal of Medical Microbiology·Farrokh Akbari NakhjavaniAkbar Mirsalehian
Jul 11, 2012·FEMS Immunology and Medical Microbiology·Teresa Estrada-Garcia, Fernando Navarro-Garcia
Jan 27, 2016·BMC Infectious Diseases·Babatunde W OdetoyinIruka N Okeke
Feb 21, 2019·Arquivos De Gastroenterologia·Roger Lafontaine Mesquita TabordaNajla Benevides Matos

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