Abstract
Eighty-two consecutive Caucasian adults (52 males, 30 females, aged 17-86 years) with membranous glomerulonephritis were prospectively evaluated for possible aetiological factors 1-4 weeks after renal biopsy. Presumed causes were identified in 17 patients (21%) as follows: drugs in five (D-penicillamine 3, captopril 1, fenoprofen 1); malignancy in four; chronic thyroiditis in three; systemic lupus erythematosus (SLE) in two; secondary syphilis in one; hepatitis B virus (HBV) infection in one and non-insulin-dependent diabetes mellitus in one patient. Except for age (patients with secondary membranous glomerulonephritis were older), clinical presentation and histological stage distribution did not differ between the secondary and the primary groups. Ten out of the 17 patients with secondary membranous glomerulonephritis (59%) achieved complete clinical remission within 12 months. The incidence of associated conditions in adults with membranous glomerulonephritis in this study corresponds with that reported in the few previous series. Although membranous glomerulonephritis is deemed to be idiopathic in most cases, it seems warranted to search for medication, malignancy, SLE, HBV infection, syphilis and thyroiditis as possible aet...Continue Reading
Citations
Jan 1, 1995·Renal Failure·F Keller, A Schwarz
Aug 4, 2007·Acta Clinica Belgica·N Lameire
Mar 1, 1990·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·J S Cameron
Dec 3, 2004·Journal of the American Society of Nephrology : JASN·Benjamin D HumphreysColm C Magee
Feb 13, 2004·Journal of Pediatric Endocrinology & Metabolism : JPEM·Friederike IlliesPeter F Hoyer
Jul 3, 2013·Journal of the American Society of Nephrology : JASN·Jicheng LvHong Zhang
Sep 23, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Gregory M LucasUNKNOWN HIV Medicine Association of the Infectious Diseases Society of America
May 31, 2017·Pflügers Archiv : European journal of physiology·Elion HoxhaRolf A K Stahl
Oct 17, 2019·The International Journal of Biological Markers·Dan ZhangJun Zou
Dec 15, 1991·Hospital Practice·K E Stone, M E Moore
Jul 18, 2006·The Journal of Small Animal Practice·C S Mansfield, C T Mooney
Mar 25, 2016·Oncotarget·Zhonglin FengBin Zhang
May 31, 2018·The New England Journal of Medicine·Charles A MorrisRicard Masia
Feb 5, 2008·Journal of Medical Case Reports·Claudia HandtrackWalter Geissdörfer
Jul 6, 2014·Clinical and Experimental Nephrology·Ramin SamMelvin M Schwartz
Oct 27, 2015·Journal of Nephrology·Antonello PaniClaudio Ponticelli
Jun 19, 2015·Nephrology·Ping ZhuHai-Yan Wang
Jul 20, 1999·Kidney International·P M Ronco
Aug 31, 2006·Kidney International·C LefaucheurUNKNOWN GN-PROGRESS Study Group
Aug 28, 2007·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rune BjørneklettBjarne M Iversen
Sep 16, 2008·Critical Reviews in Oncology/hematology·Justine BacchettaJean-Pierre Droz
Sep 7, 2007·Mayo Clinic Proceedings·Thushan I de SilvaDavid H Dockrell
Aug 1, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Anjali A SatoskarTibor Nadasdy
Nov 3, 2021·Journal of Biochemical and Molecular Toxicology·Lan HuangGui-Cai Hu