Afferent-mediated modulation of the soleus muscle activity during the stance phase of human walking.

Experimental Brain Research
Nazarena MazzaroThomas Sinkjaer

Abstract

The aim of this study was to investigate the contribution of proprioceptive feedback to the amplitude modulation of the soleus muscle activity during human walking. We have previously shown that slow-velocity, small-amplitude ankle dorsiflexion enhancements and reductions applied during the stance phase of the step cycle generate, respectively, increments and decrements on the ongoing soleus activity. We have also shown that the increments in soleus activity are at least partially mediated by feedback from group Ia fibres. In the present study, we further investigated the afferent-mediated contribution from muscle group II afferents, cutaneous and proprioceptive afferents from the foot, and load-sensitive afferents to the soleus EMG. Slow-velocity, small-amplitude ankle trajectory modifications were combined with the pharmaceutical depression of group II polysynaptic pathways with tizanidine hydrochloride, anaesthetic blocking of sensory information from the foot with injections of lidocaine hydrochloride, and modulation of load feedback by increasing and decreasing the body load. The depression of the group II afferents significantly reduced the soleus response to the ankle trajectory modifications. Blocking sensory feedback f...Continue Reading

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Citations

Aug 19, 2006·Experimental Brain Research·Yasuhiro OsakiTheodore Raphan
Oct 31, 2006·Experimental Brain Research·Rebecca H StoloffDaniel P Ferris
Oct 24, 2007·Experimental Brain Research·Yasuhiro OsakiTheodore Raphan
Nov 6, 2008·Experimental Brain Research·Hilmi UysalCumhur Ertekin
Nov 14, 2008·Journal of Neurophysiology·Kyla T Ross, T Richard Nichols
Dec 17, 2008·Journal of Neurophysiology·Monica A GorassiniJaynie F Yang
Feb 29, 2008·Experimental Brain Research·V BachmannV Dietz
Aug 2, 2008·The Journal of Physiology·Richard af KlintMichael J Grey
Sep 14, 2010·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Neil J CroninThomas Sinkjaer
Aug 11, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Nazarena MazzaroThomas Sinkjaer
Jun 15, 2007·Brain Research Bulletin·U Windhorst
Nov 22, 2014·Frontiers in Human Neuroscience·Vito Enrico Pettorossi, Marco Schieppati
Mar 19, 2014·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Aiko K Thompson, Jonathan R Wolpaw
Feb 7, 2014·Journal of Neurophysiology·Berthe Hanna-BoutrosVéronique Marchand-Pauvert
Jul 17, 2019·Experimental Brain Research·Aiko K ThompsonJ B Andersen
Jan 1, 2016·Journal of Neurophysiology·Natalie Mrachacz-KerstingDario Farina
Oct 14, 2017·Somatosensory & Motor Research·Augusta SilvaFilipa Sousa
Jan 12, 2021·Journal of the Peripheral Nervous System : JPNS·Guido FelicettiMarco Schieppati

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