Aflatoxin B1 degradation by salt tolerant Tetragenococcus halophilus CGMCC 3792

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
Jianlong LiRongqing Zhou

Abstract

This study explores aflatoxin B1 (AFB1) degradation by salt tolerant Tetragenococcus halophilus CGMCC 3792 (T. halophilus CGMCC 3792). Six non-toxic degradation products of AFB1 were identified by liquid chromatography/time-of-flight mass spectrometry (LC/TOF-MS), including m/z 243.06 (C14H10O4), 361.09 (C18H16O8), 229.09 (C14H12O3), 277.14 (C16H20O4), 217.12 (C14H16O2), 221.15 (C14H20O2). Two pathways were proposed based on molecular formulas and MS/MS spectra, and the final degradation product was m/z 221.15 (C14H20O2). The degradation ratio of active cell component (66%) and intracellular component (57%) was significantly higher than extracellular component (14%). AFB1 degradation ratio of intracellular component, initially at around 60%, was decreased to 32% after proteinase K treatment, and to 7% after heating, to 9% after proteinase K plus SDS treatment, and to 16% after TFA treatment. It suggests that the AFB1 removal mainly resulted from enzyme biodegradation. The degradation ratio was 92% in AFB1 polluted soy sauce mash. The high degradation ratio of AFB1 by T. halophilus CGMCC 3792 indicates its great potential for application in oriental fermentation condiment process.

Citations

Jan 14, 2021·Toxins·Yun GuanKamil Kuca
Apr 30, 2020·Toxicon : Official Journal of the International Society on Toxinology·Fadia Ben TaheurKamel Chaieb
Dec 28, 2021·Critical Reviews in Food Science and Nutrition·Vishal KumarMyunghee Kim

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