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AFM images of open and collapsed states of yeast condensin suggest a scrunching model for DNA loop extrusion

bioRxiv

Dec 13, 2019

Je-Kyung RyuCees Dekker

Abstract

Structural Maintenance of Chromosome (SMC) protein complexes are the key organizers of the spatiotemporal structure of chromosomes. The condensin SMC complex, which compacts DNA during mitosis, was recently shown to be a molecular motor that extrudes large loops of DNA. The mechanism of...read more

Mentioned in this Paper

Mitosis
DNA Sequence
Structure
DNA, Double-Stranded
Microscopy, Atomic Force
Entire Ginglymus
Chromosomes
Maintenance of Chromosome Localization
Protein Conformation
Condensin complexes
44
Paper Details
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AFM images of open and collapsed states of yeast condensin suggest a scrunching model for DNA loop extrusion

bioRxiv

Dec 13, 2019

Je-Kyung RyuCees Dekker

PMID: 990867358

DOI: 10.1101/2019.12.13.867358

Abstract

Structural Maintenance of Chromosome (SMC) protein complexes are the key organizers of the spatiotemporal structure of chromosomes. The condensin SMC complex, which compacts DNA during mitosis, was recently shown to be a molecular motor that extrudes large loops of DNA. The mechanism of...read more

Mentioned in this Paper

Mitosis
DNA Sequence
Structure
DNA, Double-Stranded
Microscopy, Atomic Force
Entire Ginglymus
Chromosomes
Maintenance of Chromosome Localization
Protein Conformation
Condensin complexes
44

Similar Papers Found In These Feeds

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

AFM in situ DNA

AFM in situ DNA describes in situ analysis (or study) of DNA using atomic force microscopy. Discover the latest research on AFM in situ DNA here.

Related Papers

Current Biology : CB

Towards a Unified Model of SMC Complex Function

Current Biology : CBNovember 7, 2018
Markus HasslerChristian H Haering
Paper Details
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  • finger pointing at paper

    References currently unavailable

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