AFM in peak force mode applied to worn siloxane-hydrogel contact lenses

Colloids and Surfaces. B, Biointerfaces
Clara AbadíasJ Torrent-Burgués

Abstract

The objective of this work is to apply Atomic Force Microscopy in Peak Force mode to obtain topographic characteristics (mean roughness, root-mean-square roughness, skewness and kurtosis) and mechanical characteristics (adhesion, elastic modulus) of Siloxane-Hydrogel Soft Contact Lenses (CLs) of two different materials, Lotrafilcon B of Air Optix (AO) and Asmofilcon A of PremiO (P), after use (worn CLs). Thus, the results obtained with both materials will be compared, as well as the changes produced by the wear at a nanoscopic level. The results show significant changes in the topographic and mechanical characteristics of the CLs, at a nanoscopic level, due to wear. The AO CL show values of the topographic parameters lower than those of the P CL after wear, which correlates with a better comfort qualification given to the former by the wearers. A significant correlation has also been obtained between the adhesion values found after the use of the CLs with tear quality tests, both break-up-time and Schirmer.

References

Dec 1, 1987·Leprosy Review·E J HodgesR H Gelber
Jul 1, 1969·Archives of Ophthalmology·O P van Bijsterveld
May 18, 2000·Archives of Ophthalmology·R M SchiffmanB L Reis
May 18, 2007·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Vilém GurycaJirí Michálek
Oct 25, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·M LiraM Elisabete C D Real Oliveira
Mar 5, 2009·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Carol Lakkis, Stephen Vincent
May 18, 2010·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Maria J GiraldezEva Yebra-Pimentel
Apr 6, 2013·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Michela BettuelliStefano Farris
Jul 6, 2014·Colloids and Surfaces. B, Biointerfaces·J Torrent-Burgués, F Sanz

❮ Previous
Next ❯

Citations

Jan 13, 2018·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Nejla B ErdalMinna Hakkarainen
Jul 9, 2017·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Michael SamsomTannin A Schmidt
May 27, 2021·Microscopy Research and Technique·Ştefan Ţălu
Jul 10, 2017··Igor SokolovPiers M. Echols-Jones

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Colloids and Surfaces. B, Biointerfaces
J Torrent-Burgués, F Sanz
Journal of Biomedical Materials Research. Part B, Applied Biomaterials
José M González-MéijomeManuel A Parafita
Journal of Biomedical Materials Research. Part B, Applied Biomaterials
José M González-MéijomeMiguel F Refojo
Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
B ZschauschB Heisig-Salentin
© 2022 Meta ULC. All rights reserved