PMID: 6170422Dec 1, 1981Paper

AFP in yolk sac tumor and solid teratoma of the ovary: significance of postoperative serum AFP

Cancer
T IshiguroH Suzuki

Abstract

Serial serum alpha-fetoprotein (AFP) was examined postoperatively in five patients with yolk sac tumor and in three with solid teratoma of the ovary. Serial estimation of AFP was also done in sera from postpartum patients to compare the decreasing ratio between the two groups. Serum AFP in these postpartum women decreased according to the exponential function curve as AFP = be-mx (x = days after delivery) with a mean m value of 0.1652 and a mean correlation coefficient of -0.9911. Half-time of serum AFP in postpartum subjects was 4.33 days. Exponential decrease of serum AFP was also found in postoperative patients with yolk sac tumor and solid teratoma of the ovary. However, in those in whom there was an incomplete removal of the tumors, the values of either m or coefficient of correlation were significantly lower as compared to those in patients with complete extirpation of lesions or those in postpartum subjects. Elevation of serum AFP was noted postoperatively in two patients with recurrences; however, significant decreases in AFP following chemotherapy were apparent in one patient with immature solid teratoma. These findings suggest that the decreasing ratio of postoperative serum AFP is an effective indicator to determine ...Continue Reading

References

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Citations

Aug 1, 1996·Journal of Pediatric Surgery·A M DavidoffL Schnaufer
Aug 4, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·C KliegerD Grisaru
Feb 24, 2009·Archives of Gynecology and Obstetrics·I PafilisA Antsaklis
Jun 2, 2009·Journal de gynécologie, obstétrique et biologie de la reproduction·M KehilaH Khairi
Apr 2, 2008·Cancer Treatment Reviews·D PectasidesD Kassanos
Jul 1, 1990·Gynecologic Oncology·A LopesJ M Monaghan
Sep 26, 2006·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P DällenbachG Vlastos
Apr 1, 1984·American Journal of Reproductive Immunology : AJRI·T IshiguroI Sugitachi
Oct 1, 1987·Cancer·E Nelson, P Stenzel
Oct 28, 2018·Clinical Chemistry and Laboratory Medicine : CCLM·Simona FerraroMauro Panteghini
Jan 1, 2017·Pediatric Transplantation·Taiichi WakiyaKenichi Hakamada
Mar 3, 2020·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·P AnfelterE Epstein
Jan 1, 1988·Pediatric Hematology and Oncology·C M WalhofJ F Delemarre
Jun 29, 2011·Bulletin du cancer·Caroline EvenThibault de La Motte Rouge

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