Ag-loaded mesoporous bioactive glasses against Enterococcus faecalis biofilm in root canal of human teeth

Dental Materials Journal
Wei FanBing Fan

Abstract

Ag-loaded mesoporous bioactive glass (Ag-MBG) powders were synthesized and characterized. The ions release of Ag-MBGs in Tris-HCl and the pH stability of simulated body fluids after immersing Ag-MBGs were tested. Root canals were inoculated with Enterococcus faecalis for 4 weeks, and the antibacterial activity of MBGs, Ag-MBGs and calcium hydroxide against E. faecalis biofilm were evaluated. Results showed that Ag-MBGs possessed highly ordered mesoporous structure with silver nanoparticles deposited in the mesopores, which enabled a sustained Ag ions released. The biofilms treated with Ag-MBGs showed a significant structural disruption compared with MBGs. These results indicated that Ag-MBGs possess a potent antibacterial effect against E.faecalis biofilm in root canal, and the antibacterial activity was induced by the release of Ag ions from Ag-MBGs.

References

Nov 7, 1999·International Endodontic Journal·J F Siqueira, H P Lopes
May 3, 2002·International Endodontic Journal·M EvansD Figdor
Aug 24, 2002·International Endodontic Journal·I PortenierM Haapasalo
May 6, 2004·Acta Odontologica Scandinavica·Ari-Pekka ForsbackJukka I Salonen
Sep 25, 2004·Journal of Materials Science. Materials in Medicine·M CatauroA Marotta
Jan 22, 2005·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·P N R NairJorge Vera
Feb 2, 2006·Biomaterials·Tadashi Kokubo, Hiroaki Takadama
Mar 21, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Matthias ZehnderEva Söderling
Jul 11, 2007·Journal of Materials Science. Materials in Medicine·Outi LeppärantaErkki Eerola
Apr 15, 2008·Dental Materials : Official Publication of the Academy of Dental Materials·A BalamuruganJ M F Ferreira
Jan 22, 2011·Chemical Communications : Chem Comm·Zhangxiong Wu, Dongyuan Zhao
May 4, 2011·International Endodontic Journal·Z Mohammadi, P M H Dummer
May 29, 2013·Journal of Materials Science. Materials in Medicine·Nicola GargiuloPaolo Antonio Netti
Mar 13, 2014·Dental Materials Journal·Yusuke MoritaYoshiki Nakamura
Apr 17, 2014·Journal of Biomedical Materials Research. Part a·A ManchónE López-Cabarcos

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Citations

Dec 18, 2015·Journal of Materials Science. Materials in Medicine·Wei FanBing Fan
Aug 12, 2017·International Journal of Molecular Sciences·Prasanna NeelakantanGary Shun Pan Cheung
Sep 11, 2018·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Vincenzo FaranoKerstin Gritsch
Jan 7, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Sara PourshahrestaniMark R Towler
Dec 4, 2020·Emerging Topics in Life Sciences·Joanna Shepherd
Sep 21, 2020·Journal of Endodontics·Juliana S RibeiroMarco C Bottino
Mar 18, 2021·International Journal of Nanomedicine·Jasmine WongChengfei Zhang
Apr 4, 2021·International Journal of Molecular Sciences·Clara Couto FernandezLjubica Tasic

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