PMID: 8594148Nov 1, 1995Paper

Agastaquinone, a new cytotoxic diterpenoid quinone from Agastache rugosa

Journal of Natural Products
H K LeeC O Lee

Abstract

A new diterpenoid quinone, agastaquinone [1], was isolated from the roots of Agastache rugosa. An oxime derivative [2] of agastaquinone was prepared with hydroxylamine hydrochloride. The structure of agastaquinone [1] was established as 7-hydroxy-12-methoxy-20-norabieta-1,5(10),6,8,12-pentaene-3,11,14- trione by spectroscopic techniques. Compounds 1 and 2 showed nonspecific cytotoxic activities against several human cancer cell lines in vitro (A549, SK-OV-3, SK-MEL-2, XF498, and HCT15).

Citations

Mar 11, 1999·Archives of Pharmacal Research·B S MinY H Kim
Nov 5, 1999·Archives of Pharmacal Research·H K KimH Huh
May 29, 2012·Journal of Agricultural and Food Chemistry·Pham Anh TuanSang Un Park
Jun 6, 2014·Phytochemistry Reviews : Proceedings of the Phytochemical Society of Europe·Sylwia Zielińska, Adam Matkowski
Apr 5, 2002·Phytotherapy Research : PTR·Byung-Sun MinMasao Hattori
Mar 27, 2018·Oxidative Medicine and Cellular Longevity·K BeckerJ M Gostner
Feb 9, 2017·BMC Complementary and Alternative Medicine·Pengran CaoWen-Yi Kang

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