Age- and gender-specific mortality risk profiles for depressive outpatients with major chronic medical diseases

Journal of Affective Disorders
Ingeborg WarnkeWulf Rössler

Abstract

As leading causes of death, chronic medical diseases, particularly common cardiovascular diseases, are associated with depression. The combination of depression and chronic medical disease in turn is linked with poorer health and premature death. Despite numerous studies on mortality in people with depression and chronic medical disease, the effects of age and gender were not consistently considered. To appropriately estimate mortality in the clinical setting, we aimed to analyse age- and gender-specific mortality profiles in outpatients with depression and chronic medical disease by considering depression severity. We examined data from N=327,018 outpatients with depression aged 18 years and older (mean=60 years), which we obtained from German electronic health-insurance claims data covering the years 2007-2010. We considered major chronic medical disease groups: cardiovascular diseases, diabetes, diseases of the respiratory system and cancer. To analyse both adjusted mortality risk and rates over one year in a comprehensive manner, we calculated General Estimation Equation (GEE) Poisson models for binary data. The mortality risk increased with age and was higher for males. Especially patients below 60 years of age with cancer...Continue Reading

References

Oct 20, 1993·JAMA : the Journal of the American Medical Association·N Frasure-SmithM Talajic
Nov 27, 2002·Journal of Affective Disorders·Pim Cuijpers, Filip Smit
Nov 27, 2004·Psychosomatic Medicine·Susan A Everson-RoseRichard P Mero
May 2, 2007·Psychosomatic Medicine·Arnstein MykletunRobert Stewart
Sep 16, 2009·Annals of Family Medicine·Elizabeth H B LinMichael Von Korff
Jan 21, 2010·Psychological Medicine·M Pinquart, P R Duberstein
Jan 5, 2011·Archives of General Psychiatry·An PanFrank B Hu
Feb 26, 2014·Circulation·Judith H LichtmanUNKNOWN American Heart Association Statistics Committee of the Council on Epidemiology and Prevention and the Council on Cardiovascu
Aug 21, 2014·BMC Endocrine Disorders·Cheryl P LynchLeonard E Egede
Nov 25, 2014·International Journal of Chronic Obstructive Pulmonary Disease·Maria PanagiotiPeter A Coventry
May 23, 2015·The Lancet. Diabetes & Endocrinology·Frank PetrakRichard I G Holt

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disorder in Diabetes

Diabetes is associated with an increased risk of cardiovascular disorders and heart failure. Discover the latest research here.

Related Papers

MMWR Supplements
Cathleen D GillespieCenters for Disease Control and Prevention (CDC)
Journal of the American College of Nutrition
Hana CastelIlana Harman-Boehm
Lung Cancer : Journal of the International Association for the Study of Lung Cancer
Andrea EberleGEKID Survival Working Group
© 2022 Meta ULC. All rights reserved