Age and gender related differences in renal cell carcinoma in a European cohort

The Journal of Urology
M N HewM Pilar Laguna

Abstract

We evaluated the influence of age on gender related differences in the renal cell carcinoma presentation of patients operated on between 1995 and 2005 in a European country. We also assessed the trend of missing pathological data. Data on all patients who underwent radical or partial nephrectomy for renal cell carcinoma during 1995 to 2005 in The Netherlands were retrospectively collected from the prospective PALGA (Pathological Anatomical National Automated Archive) database. Patients were divided into 5 cohorts based on age at surgery, including 40 or less, 41 to 50, 51 to 60, 61 to 70 and greater than 70 years. Variables evaluated were gender differences by age, and tumor size, subtype, stage and Fuhrman grade. A higher mean age in women was only observed in those older than 70 years (p <0.001). The male-to-female ratio was 2:1 at ages 41 to 60 years and 1.2:1 at greater than 70 years. Compared to men women had smaller tumors at ages 51 to 60 years (p = 0.03), stage pT3 was less common at age 41 years or greater (p = 0.02), and grade 2 was less common at age 61 years or greater (p <0.001). The incidence of tumors with missing data on stage (14.9%), subtype (52.2%) and grade (47.1%) decreased substantially during the study pe...Continue Reading

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Citations

Apr 10, 2013·World Journal of Urology·Frank KunathMaximilian Burger
Jan 15, 2014·Virchows Archiv : an International Journal of Pathology·Mahmoud AbbasKais Hussein
Apr 10, 2013·World Journal of Urology·Matthias MayUNKNOWN Members of the CORONA project the Young Academic Urologists Renal Cancer Group
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Jun 20, 2020·European Journal of Radiology·Andreas M HötkerOguz Akin

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