PMID: 2114801Aug 1, 1990Paper

Age and human immunodeficiency virus infection in persons with hemophilia in California

American Journal of Public Health
R C HolmanB L Evatt

Abstract

Thirteen hemophilia centers provide comprehensive care to approximately 90 percent of persons with hemophilia in California. For 1987, these centers reported patient human immunodeficiency virus (HIV) antibody status, age group, level of clotting factor deficiency, and hemophilia type on 1,438 persons with hemophilia A and B; HIV serologic status was known for 860 persons (59.8 percent) of whom 537 (62.4 percent) were HIV-antibody-positive. The HIV positivity rate increased with age after taking into account hemophilia type, clotting factor level and treatment center type. The three-year cumulative incidence of reported AIDS (acquired immunodeficiency syndrome) cases based on the number of HIV positive patients, was 11.6 percent. The cumulative incidence rate was 14.6 percent (54 of 370) for those patients over 20 years of age and 4.8 percent (8 of 167) for those under 21 years of age. Although a comparable distribution of the date of diagnoses of AIDS was seen by age group, there appeared to be a bimodal distribution in the rate of AIDS among the age groups, with the 6-12-year-olds and the 21 and older age groups showing higher incidence rates.

References

Feb 21, 1985·The New England Journal of Medicine·B L EvattR B Ramsey
Apr 19, 1985·JAMA : the Journal of the American Medical Association·M E EysterW A Blattner
Apr 1, 1988·American Journal of Public Health·J K Stehr-GreenB L Evatt
Oct 8, 1987·Nature·H Ekert
Dec 24, 1987·Nature·M J TurnerW P Soutter

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Citations

Dec 1, 1996·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·A S RogersL D'Angelo
Jan 9, 2001·Clinical Microbiology Reviews·R S BonevaL E Chapman
Feb 1, 1994·American Journal of Hematology·T L ChorbaB L Evatt

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