Age and pattern of the onset of differential growth among growth plates in rats.

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
N J WilsmanC E Farnum

Abstract

Differential growth is the phenomenon whereby growth plates in the same individual at the same time all have uniquely different axial growth velocities. Differential growth is clearly present in the adolescent skeleton. In this study we ask two questions. When and by what pattern does the phenomenon of differential growth begin? Second, to what extent are the development of differential growth velocities correlated with changes in hypertrophic chondrocyte volume and/or with changes in chondrocytic production/turnover? Four growth plates (proximal and distal radial; proximal and distal tibial) were studied at 24 different time points in Long-Evans rats between the 17th gestational day (when differential growth does not exist) and postnatal day 27 (when differential growth is well established). Growth velocities were measured using fluorochrome labeling. Using stereological methodology, multiple chondrocytic kinetic parameters were measured for all growth plates. Elongation of the proximal radial growth plate decreases relative to elongation in the other three growth plates in the late fetal phase. Differential growth is fully expressed at postnatal day 13 when the other three growth plates start to decrease daily elongation at d...Continue Reading

References

Sep 1, 1978·Cell and Tissue Kinetics·N F Kember
May 1, 1991·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G J BreurN J Wilsman
Jul 1, 1989·The Journal of Physiology·E B Hunziker, R K Schenk
May 1, 1988·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·H J GundersenA Vesterby
Jul 1, 1986·Journal of Microscopy·L M Cruz-Orive, E B Hunziker
May 15, 1970·Experientia·B A Rahn, S M Perren
Jul 1, 1996·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·N J WilsmanM K Clayton
Nov 1, 1996·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·N J WilsmanC Barreto
May 1, 1997·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·J A Germiller, S A Goldstein
Sep 25, 1998·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·K J NoonanJ A Buckwalter
May 16, 2003·Nature·Henry M Kronenberg
Oct 17, 2003·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Dennis R Carter, Marcy Wong
Sep 25, 2004·Journal of Cellular Physiology·Frank Beier
Oct 27, 2004·Journal of Pediatric Orthopedics·Kenneth J NoonanNorman J Wilsman
Dec 1, 2004·Frontiers in Bioscience : a Journal and Virtual Library·Tian-Fang LiDi Chen
Oct 29, 2005·American Journal of Human Biology : the Official Journal of the Human Biology Council·Shelley L Smith, Peter H Buschang
Jan 26, 2006·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Sona Sundaramurthy, Jeremy J Mao
May 13, 2006·Biomechanics and Modeling in Mechanobiology·C C van Donkelaar, R Huiskes

❮ Previous
Next ❯

Citations

Mar 24, 2009·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Elizabeth A NorgardJames M Cheverud
Dec 23, 2008·Journal of Pediatric Orthopedics·Jason M SansoneKenneth J Noonan
Feb 18, 2011·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Thomas J SangerJames M Cheverud
Oct 13, 2012·Journal of Cellular Biochemistry·Mohamad Y LoqmanAndrew C Hall
Mar 5, 2010·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Peter G BushAndrew C Hall
Feb 3, 2015·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Maria A SerratHolly L Tamski
Jul 28, 2012·Annals of Human Biology·Michelle Lampl
Nov 15, 2013·Autophagy·Irving M ShapiroCaroline Whitehouse
Jun 25, 2017·The Spine Journal : Official Journal of the North American Spine Society·Adalbert RaimannGabriele Haeusler
Aug 12, 2017·Journal of Applied Physiology·Maria A Serrat, Gabriela Ion
Jun 11, 2019·Integrative and Comparative Biology·Kimberly L Cooper
Apr 25, 2019·Animal Models and Experimental Medicine·Adamu Abdul AbubakarLoqman Mohamad Yusof
May 18, 2020·Current Osteoporosis Reports·Holly L Racine, Maria A Serrat
Jun 20, 2018·Frontiers in Endocrinology·Holly L RacineMaria A Serrat
Dec 29, 2020·Experimental Physiology·Elaine Zhou, Julian Lui

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
G J BreurN J Wilsman
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
N J WilsmanM K Clayton
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
N J WilsmanC Barreto
The Journal of Bone and Joint Surgery. American Volume
E B HunzikerL M Cruz-Orive
© 2022 Meta ULC. All rights reserved