Age-associated changes in granulosa cells and follicular fluid in cows

The Journal of Reproduction and Development
H Iwata

Abstract

Age-associated decline in oocyte quality is common in mammals. Oocytes take a long time to reach their full-grown size in large animals, and maternal physical conditions profoundly affect follicle development. Aging affects the oocyte itself as well as the surrounding environment, such as granulosa cells and follicular fluid. This review discusses age-associated changes that occur in granulosa cells and follicular fluid in cows and suggests that age-associated decline in granulosa cells and follicular fluid hampers proper oocyte development.

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Citations

Sep 15, 2020·The Journal of Reproduction and Development·Shuta NagataHisataka Iwata
Feb 9, 2021·The Journal of Reproduction and Development·Tatsuya NakanoTasuku Mitani
Jun 8, 2021·Aging and Disease·Chia-Jung LiKuan-Hao Tsui
Jul 11, 2021·Mechanisms of Ageing and Development·Lucía Chico-SordoElisa Varela
Nov 20, 2021·Animal Science Journal = Nihon Chikusan Gakkaihō·Yanjun ZhangMingjiu Luo

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Methods Mentioned

BETA
histone acetylation
RNA-seq
acetylation
ELISA

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