Age-associated changes in nicotine dependence

Public Health
Sang Min ParkS-I Cho

Abstract

Nicotine is the primary factor responsible for tobacco dependence among individuals who smoke. Nicotinic receptors and nicotine-associated metabolism, two significant aspects of nicotine dependence, are influenced by age. To date, however, the relationship between age and nicotine dependence has not been investigated. Cross-sectional. Data were obtained from the national smoking cessation programme for South Korea. Data obtained from current smokers in 2008 (n = 338,566) were used as baseline measures. Nicotine dependence was determined by the Fagerström Test for Nicotine Dependence (FTND). Cigarettes per day (CPD) and FTND were the dependent variables. As CPD is a major component of FTND, scores on the FTND minus scores related to CPD were also used as a dependent variable. The relationships between age and the dependent variables (FTND, CPD, partial FTND) were investigated. Quadratic regression models were used to test the non-linear relationship between age and nicotine dependence after adjusting for other covariates. Analyses relying on nicotine dependence (FTND and partial FTND scores) and CPD produced similar results in relation to age. Specifically, the values of all three dependent variables increased with age until app...Continue Reading

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Citations

Feb 12, 2014·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Matthew R CostelloFrances M Leslie
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Jan 3, 2018·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Po-Yin ChangTsuo-Hung Lan

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