Age-associated impairement in endpoint accuracy of goal-directed contractions performed with two fingers is due to altered activation of the synergistic muscles

Experimental Gerontology
Yen-Ting ChenEvangelos A Christou

Abstract

The purpose of this study was to determine whether older adults compared with young adults exhibit impaired end-point accuracy during a two-finger task due to altered activation of the contributing synergistic muscles. Nine young (21.3 years ± 1.6 years, 4 men) and 9 older (73.1 years ± 6.4 years, 5 men) were instructed to accurately match the center of a target with concurrent abduction of the index and little fingers (synergistic two-finger task). The target comprised of 20% MVC and 200 ms. Visual feedback of the force trajectory and target was provided 1s after each trial. Subjects completed 40 trials and the last 10 were used for analysis. Endpoint accuracy was quantified as the normalized deviation from the target in terms of peak force (peak force error), time-to-peak force (time-to-peak force error), and a combination of the two (overall error). Motor output variability was quantified as the standard deviation and coefficient of variation (CV) of peak force and time to peak force. The neural activation of the involved synergist muscles (first dorsal interosseus (FDI) and abductor digiti minimi (ADM)) was quantified with the electromyography (EMG) amplitude (root mean square) and its frequency structure (wavelet analysis)...Continue Reading

References

Apr 1, 1980·Journal of the Neurological Sciences·G HendersonP H Gibson
Dec 22, 1999·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·T Mima, M Hallett
Jan 6, 2000·Progress in Neurobiology·P Brown
Dec 19, 2002·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Roger M EnokaBrian L Tracy
Mar 11, 2003·Journal of Applied Physiology·Minoru ShinoharaVladimir M Zatsiorsky
Oct 29, 2003·Clinical Biomechanics·Zong-Ming LiSavio L-Y Woo
Mar 16, 2004·Journal of Applied Physiology·Dario FarinaRoger M Enoka
Jul 23, 2004·Journal of Neurophysiology·John G SemmlerMichael A Nordstrom
Feb 24, 2005·Experimental Brain Research·Fan GaoVladimir M Zatsiorsky
Aug 5, 2006·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Claudia Voelcker-RehageJay L Alberts
Oct 19, 2006·Clinical Biomechanics·Halla OlafsdottirMark L Latash
Nov 3, 2006·Physical Therapy·Yaron BarakKenneth G Holt
Mar 23, 2007·Journal of Neurophysiology·Evangelos A ChristouRoger M Enoka
Apr 25, 2007·Perceptual and Motor Skills·Alexandra Perrot, Jean Bertsch
Apr 22, 2008·Experimental Brain Research·Elena Yu ShapkovaMark L Latash
Dec 25, 2009·Journal of Neurophysiology·Osmar Pinto Neto, Evangelos A Christou
Mar 5, 2010·British Medical Bulletin·Marco V Narici, Nicola Maffulli
Sep 11, 2010·Journal of Applied Physiology·Shweta KapurMark L Latash
Oct 15, 2010·Age·Evangelos A Christou, Roger M Enoka
Nov 16, 2010·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Vinzenz von TscharnerLisa M Stirling
Jan 6, 2011·Exercise and Sport Sciences Reviews·Evangelos A Christou
Nov 29, 2011·Journal of Neuroscience Methods·Verity M McClellandKerry R Mills

❮ Previous
Next ❯

Citations

Feb 22, 2014·Experimental Brain Research·MinHyuk KwonEvangelos A Christou
Jun 8, 2014·European Journal of Applied Physiology·Emily J FoxEvangelos A Christou
Mar 5, 2016·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Neha LodhaEvangelos A Christou
Aug 25, 2015·Experimental Brain Research·Harsimran S BawejaEvangelos A Christou
Jul 18, 2015·PloS One·Tanya OnushkoAllison Hyngstrom
Nov 6, 2014·PloS One·Hwasil MoonEvangelos A Christou
May 23, 2014·Journal of Neurophysiology·Yen-Ting ChenEvangelos A Christou
Apr 23, 2016·Journal of Applied Physiology·Awad M AlmuklassRoger M Enoka
Mar 11, 2016·Journal of Neurophysiology·Seoung Hoon ParkEvangelos A Christou
Jun 14, 2017·Experimental Brain Research·Seoung Hoon ParkEvangelos A Christou
Apr 9, 2021·Scientific Reports·Stefan DelmasEvangelos A Christou

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.