Age at onset of bipolar disorder in a Norwegian catchment area sample

Journal of Affective Disorders
Sara LarssonOle A Andreassen

Abstract

Early onset of bipolar disorder (BD) is an important clinical predictor of a more severe course and poorer outcome. A higher proportion of childhood onset BD has been reported in studies from USA compared to Europe. We investigated age at onset of first affective episode in a Norwegian sample and compared it to previous European and US findings. In addition, we examined whether age at onset influenced on time to first treatment, and if patient characteristics related to illness severity influenced age at onset. Two hundred and twenty five BD patients were recruited consecutively mainly from psychiatric out-patient units at three major hospitals in Oslo, Norway, diagnosed using SCID-I and divided into four groups based on age at onset. Six percent of the patients had onset in childhood, 32% in adolescence, 43% in young adulthood, and 19% as adults. Average age at onset was 22.8 years (SD 9.4). There was a significantly higher age at onset and a significantly shorter time from onset to first treatment in patients with lifetime hospitalization. Retrospective information which could be confounded by collection bias. Age at onset in our sample resembled previous European studies, but not US- or Norwegian studies. The difference in a...Continue Reading

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Citations

Jan 27, 2011·European Archives of Psychiatry and Clinical Neuroscience·Trine V LagerbergIngrid Melle
Oct 2, 2012·Journal of Affective Disorders·David R ToporMartin Keller
Sep 29, 2012·Journal of Affective Disorders·Mythily SubramaniamSiow Ann Chong
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Mar 26, 2013·Bipolar Disorders·Sofie Ragnhild AminoffIngrid Melle
Mar 4, 2014·Bipolar Disorders·Sergey MosolovJules Angst
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Feb 2, 2012·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Ross J BaldessariniMauricio Tohen

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