Age at Onset, Survival Duration, and Cognitive Performance in Probable Alzheimer's Disease

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Asenath La RueL F Jarvik

Abstract

The relative importance of age at onset, survival duration past testing, symptom duration, and education as predictors of cognitive performance was assessed in 50 patients with moderately severe dementia of the Alzheimer type. Survival past testing and duration of symptoms prior to assessment emerged as the strongest predictors of cognitive performance, and education effects were noted for several verbal tests. A robust association emerged between cognitive impairment and nearness to death. This association, first noted in studies of "normal" aging, requires further exploration. Age-at-onset effects, with poorer performance in early-onset disease, were observed only for a few measures.

Citations

Jun 3, 2011·Journal of Geriatric Psychiatry and Neurology·Edmond TengLissy F Jarvik

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