Age-dependency of cardiac and neuromuscular findings in adults with left ventricular hypertrabeculation/noncompaction

The American Journal of Cardiology
Claudia StöllbergerJosef Finsterer

Abstract

Left ventricular hypertrabeculation/noncompaction (LVHT) is diagnosed in all ages and is frequently associated with neuromuscular disorders (NMDs). The aim of the study was to compare patients with LVHT depending on age at diagnosis. Included were 232 patients with LVHT (72 women, mean age 52±17 years) diagnosed from 1995 to 2014 at 1 echocardiographic laboratory. In 2014, their survival was assessed. Seventy-six percent of the patients were neurologically investigated, revealing specific NMDs in 18%, unspecific NMDs in 60%, and normal findings in 22%. Forty-five patients (19%) received electronic devices: implantable cardioverter-defibrillators in 26 patients, combined with cardiac resynchronization systems (n=14) or an antibradycardic pacemaker (n=1); antibradycardic pacemakers (n=8); cardiac resynchronization systems (n=4); implantable loop recorders (n=4); life vests (n=2); and a left ventricular assist device as a bridge to transplantation (n=1). During 72-month follow-up, mortality was 4.9% per year. In younger age groups, more patients were referred for syncope or palpitations, whereas in older age groups, more patients were referred for heart failure. Classic cardiovascular risk factors such as hypertension and diabetes...Continue Reading

References

Feb 22, 2005·International Journal of Cardiology·Tatsuya KawasakiHiroki Sugihara
Jan 30, 2010·Progress in Cardiovascular Diseases·Radha J SarmaUri Elkayam
Jan 5, 2011·European Journal of Heart Failure·Gilbert HabibUNKNOWN Working Groups 'Heart Failure and Cardiomyopathies' and 'Echocardiography' of the French Society of Cardiology
Jul 27, 2011·International Journal of Cardiology·Josef FinstererErnst Sehnal
Nov 1, 2011·The American Journal of Cardiology·Matthias GreutmannErwin N Oechslin
Apr 21, 2012·Heart & Lung : the Journal of Critical Care·Claudia StöllbergerJosef Finsterer
Feb 26, 2013·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Josef FinstererKarim Wahbi
Aug 16, 2013·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Marcello DisertoriEloisa Arbustini
Feb 26, 2016·Journal of Community Hospital Internal Medicine Perspectives·Aditya Goud, Sriram Padmanabhan

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Citations

Feb 13, 2016·Prenatal Diagnosis·Claudia Stöllberger, Josef Finsterer
Apr 29, 2015·International Journal of Cardiology·Claudia Stöllberger, Josef Finsterer
Sep 13, 2016·Iranian Journal of Pediatrics·Claudia Stollberger, Josef Finsterer
Jun 23, 2016·The American Journal of Cardiology·Claudia Stöllberger, Josef Finsterer
Jul 22, 2016·Expert Review of Cardiovascular Therapy·Claudia Stöllberger, Josef Finsterer

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