PMID: 15374393May 1, 1992Paper

Age-dependent changes in the mitochondrial F0F1 ATP synthase

Archives of Gerontology and Geriatrics
F GuerrieriS Papa

Abstract

The age dependence of ATP hydrolase activity and oligomycin sensitive passive proton conduction in sonicated submitochondrial particles of rat brain and rat heart has been investigated. The results show an increase of Vmax of the ATP hydrolase activity and decrease of oligomycin sensitive passive proton conduction with increase of the age of rats from 3 to 6 months. Decrease of ATPase activity and increase of oligomycin sensitive proton conduction occur with further aging to 24 months. Immunoblot analysis shows that both the F(1) and F(0) contents of mitochondria vary with the age of rats, the former exhibiting relatively larger changes.

References

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Citations

Nov 23, 2006·Cardiovascular Drugs and Therapy·José Marín-GarcíaMichael J Goldenthal
Oct 20, 1994·Mechanisms of Ageing and Development·C CastelluccioM Marchetti
May 1, 1993·Archives of Gerontology and Geriatrics·G ParadiesE Quagliariello
Feb 1, 1993·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·R F VillaA M Giuffrida-Stella
Apr 12, 1994·Biochimica Et Biophysica Acta·D BoffoliS Papa
Mar 9, 2000·Mechanisms of Ageing and Development·S BarogiG Lenaz
Dec 1, 1996·Molecular Aspects of Medicine·S PapaP Seibel
Jan 20, 1999·Biochimie·M N GadaletaP Cantatore
Nov 30, 1992·Annals of the New York Academy of Sciences·F GuerrieriS Papa
Mar 23, 2005·Biochemical and Biophysical Research Communications·Connie S YarianRajindar S Sohal
Jan 1, 1994·Archives of Gerontology and Geriatrics·G CapozzaS Papa
Jun 30, 1994·Annals of the New York Academy of Sciences·M N GadaletaP Cantatore
May 29, 2020·Journal of Molecular and Cellular Cardiology·Nelli Mnatsakanyan, Elizabeth Ann Jonas
Jul 13, 2020·Experimental Neurology·Nelli Mnatsakanyan, Elizabeth Ann Jonas
Sep 24, 1999·Biochemical and Biophysical Research Communications·F PolizioI Mavelli

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