Age effects on the asymmetry of the motor system: evidence from cortical oscillatory activity

Biological Psychology
Antonino VallesiDonald T Stuss

Abstract

Functional hemispheric asymmetry can be lost with aging. In this electroencephalographic study, we assessed hemispheric asymmetries in regulating motor responses by analyzing oscillatory brain activity during a go/nogo task in younger and older right-handed participants. Three conditions were embedded in the task: go, high-conflict and low-conflict nogo. The hand used to respond to go stimuli was varied block-wise. Independently of the go/nogo conditions and responding hand, young participants showed asymmetric desynchronizations in the mu (10 Hz) and beta (18-22 Hz) frequency bands that was stronger in the scalp sensorimotor region contralateral to the hand used for the go responses, while older adults showed a more symmetric pattern of desynchronization. These findings indicate that a loss of hemispheric asymmetry is a hallmark of the aging motor system, consistent with a decline of inter-hemispheric motor inhibition in normal aging.

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Citations

Jan 15, 2014·Neuropsychology Review·Joanna L BrooksStephen Darling
Nov 4, 2015·Frontiers in Aging Neuroscience·Marlene BönstrupFriedhelm C Hummel
Aug 16, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Christina Schmiedt-FehrCanan Basar-Eroglu
Jan 31, 2015·PloS One·Hadj Boumediene MezianeMaria Felice Ghilardi
Jan 10, 2012·Journal of Applied Physiology·Ashley N Johnson, Minoru Shinohara
Jan 10, 2017·Frontiers in Aging Neuroscience·Fanny QuandtFriedhelm C Hummel
Mar 3, 2020·Frontiers in Aging Neuroscience·Shane FresnozaAnja Ischebeck
Feb 23, 2020·Scientific Reports·Luisa RoederGraham K Kerr
Nov 13, 2019·NeuroImage. Clinical·Sarah Nadine MeissnerBettina Pollok
May 30, 2021·Neuroscience Letters·Yadrianna Acosta-Sojo, Bernard J Martin
Jan 11, 2020·Neuropsychologia·Shuo Qin, Chandramallika Basak

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