Age, gender, and topography influence the clinical and dermoscopic appearance of lentigo maligna

Journal of the American Academy of Dermatology
Danica Tiodorovic-ZivkovicIris Zalaudek

Abstract

Little is known about the frequency of clinical and dermoscopic patterns of lentigo maligna (LM) in relation to specific anatomic subsites and patients characteristics. We sought to assess the frequency of clinical and dermoscopic features of LM and to correlate them to specific anatomic subsites, and patients' age and gender. This was a retrospective analysis of clinical and dermoscopic images of a series of consecutive, histopathologically diagnosed, facial and extrafacial LM. A total of 201 cases from 200 patients (mean age 69.51 ± 12.26 years) including 120 women were collected. Most cases were located on the face (n = 192, 95.5%). In 102 cases, LM presented as clinically solitary facial macule (s/LM), whereas it was associated with multiple surrounding freckles in the remaining cases. s/LM were significantly smaller (<10 vs >10 mm; P = .020) and associated with younger age compared with LM associated with multiple surrounding freckles (mean age 67.73 ± 12.68 years vs 71.34 ± 11.59 years, respectively; P = .036). Dermoscopically, gray color irrespective of a specific pattern was the most prevalent finding seen in 178 (88.6%) cases. This was a retrospective study. The knowledge about patient age, patient gender, and site-rel...Continue Reading

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Citations

Feb 16, 2016·Actas dermo-sifiliográficas·L A Bollea-GarlattiR L Galimberti
Mar 22, 2016·Expert Review of Anticancer Therapy·Nora WoltscheIris Zalaudek
Jan 20, 2016·The British Journal of Dermatology·A LallasI Zalaudek
Feb 19, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·E WurmH Kittler
Oct 7, 2017·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·C MenzerH A Haenssle
Jan 18, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·E CinottiJ L Perrot
May 9, 2019·JAMA Dermatology·Angela MorenoEduardo Nagore
Apr 24, 2018·Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia·Erika V De LucaKetty Peris
Apr 19, 2019·The Australasian Journal of Dermatology·Reyes Gamo-VillegasJosé Luis López-Estebaranz
Apr 28, 2017·The Journal of Dermatology·Teresa RussoGiuseppe Argenziano
Nov 24, 2020·Clinical, Cosmetic and Investigational Dermatology·Helena IznardoOriol Yélamos
Oct 24, 2020·Journal of the American Academy of Dermatology·Cristian Navarrete-DechentKishwer S Nehal
May 8, 2021·Journal of the European Academy of Dermatology and Venereology : JEADV·F GarbarinoC Longo
Jun 22, 2021·Archives of Dermatological Research·Fernanda Berti Rocha MendesGisele Gargantini Rezze

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