PMID: 16519828Mar 8, 2006Paper

Age impact in clinicopathologic presentation and the clinical evolution of prostate cancer in patients submitted to radical prostatectomy

International Braz J Urol : Official Journal of the Brazilian Society of Urology
Alberto A AntunesMiguel Srougi

Abstract

To assess the influence of age in pathological findings and clinical evolution of prostate cancer in patients treated with radical prostatectomy. Five hundred and fifty-six patients operated on between 1991 and 2000 were selected. Patients were divided into age groups of between 10 and 49 years, 50 to 59 years, 60 to 69 years and 70 to 83 years. Patients having less than 60 years of age presented clinical stage (p = 0.001), PSA (p = 0.013) and biopsy Gleason score (p = 0.013) more favorable than older patients. Age groups did not show any relationship between either postoperative Gleason score or pathological stage or risk of non-confined organ disease and involvement of seminal vesicles. After a mean follow-up of 58.3 months, 149 (27%) patients presented recurrence. Patients aged between 40 and 59 years presented a disease-free survival rate significantly higher when compared to patients aged between 60 and 83 years (p = 0.022). However, when controlled with clinical stage, PSA, Gleason score and percentage of positive fragments, there was no relationship between age and biochemical recurrence risk (p = 0.426). Even though younger patients presented more favorable preoperative characteristics, postoperative pathological findin...Continue Reading

References

Jan 1, 1972·Journal of Surgical Oncology·D E JohnsonA G Ayala
Feb 1, 1971·The Journal of Urology·I Silber, M H McGavran
Jun 1, 1983·British Journal of Urology·G S Harrison
Jun 3, 1998·Urology·D M HeroldG E Hanks
Jan 23, 1999·The Journal of Urology·J AdolfssonP O Hedlund
May 1, 1965·The Journal of Urology·H B TJADENR H FLOCKS
Mar 19, 2004·Urology·Stephen J FreedlandUNKNOWN SEARCH Database Study Group
Jun 10, 2004·JAMA : the Journal of the American Medical Association·Jan-Erik JohanssonHans-Olov Adami

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Citations

May 3, 2005·The Urologic Clinics of North America·Richard E Hautmann, John P Stein
May 19, 2006·Expert Opinion on Therapeutic Targets·Arthur L BurnettTrinity J Bivalacqua
Oct 27, 2006·Expert Review of Medical Devices·Michael MuntenerDan Stoianovici
Feb 28, 2007·Pharmacogenomics·Glen L Hortin, Denis Sviridov
Jun 6, 2009·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Theolyn N PriceWilliam F Young
Nov 28, 2018·Journal of Ophthalmic & Vision Research·Mitra FarnoodianNader Sheibani
Mar 27, 2010·Revista de saúde pública·Arn Migowski, Gulnar Azevedo e Silva

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