Age is but a number when considering epilepsy surgery in older adults

Epilepsy & Behavior : E&B
Rebecca O'DwyerSepehr Sani

Abstract

A quarter of patients with newly diagnosed epilepsy are older, yet they are less likely to be offered resective surgery potentially because of clinical bias that they incur increased surgical risks. There are few peer-reviewed case series that address this cohort and their outcomes. In the context of current literature, the objective of this study was to report on all epilepsy surgeries in patients aged 50 years or older from a tertiary care center over 15 years with an average follow-up period of 6 years. Patients with epilepsy who underwent surgery between 2001 and 2016 were reviewed retrospectively. Inclusion criteria were age > 50 at surgery, availability of presurgical evaluation data, and minimum one year of follow-up data. We identified 34 patients. Seizure outcome was evaluated using the Engel classification system. Thirty-four patients aged 50 years and older out of 276 underwent epilepsy surgery. Average age at time of surgery was 55 years, and average duration of epilepsy was 30 years. Average length of follow-up was 6 years (1-15 years). Twenty-two out of 34 patients (64%) were seizure-free (Engel class I) at their last follow-up visit. Patients with lesional pathology on neuroimaging were more likely to achieve sei...Continue Reading

Citations

Apr 11, 2020·Therapeutics and Clinical Risk Management·Naoki IchikawaHideo Enoki
Nov 12, 2020·Seminars in Neurology·Rebecca O'Dwyer
Aug 6, 2021·Epilepsy & Behavior : E&B·Jafar Mehvari HabibabadiNasim Tabrizi

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