Age modifies the risk factor profiles for acute kidney injury among recently diagnosed type 2 diabetic patients: a population-based study.

GeroScience
Chia-Ter ChaoKuo-Liong Chien

Abstract

The incidence of acute kidney injury (AKI) rises with age and is associated with multiple risk factors. Here, we compared the risk factors for AKI between younger and older incident diabetic patients to examine the trends in risk alteration for individual factors across different age groups. Between 2007 and 2013, we selected all incident type 2 diabetic adults from the Taiwan National Health Insurance registry, stratified based on age: young (< 65 years), old (≥ 65 but < 75 years), and older-old (≥ 75 years). All factors with potential renal influence (e.g., comorbidities, medications, and diagnostics/procedures) were recorded during the study period, with a nested case-controlled approach utilized to identify independent risk factors for AKI in each age group. Totally, 930,709 type 2 diabetic patients were categorized as young (68.7%), old (17.7%), or older-old (13.6%). Older-old patients showed a significantly higher incidence of AKI than the old and the young groups. Cardiovascular morbidities (hypertension, atrial fibrillation, acute coronary syndrome, and cerebrovascular disease) were shown to increase the risk of AKI, although the risk declined with increasing age. Chronic obstructive pulmonary disease and receiving card...Continue Reading

References

Nov 20, 2004·Occupational and Environmental Medicine·D B Richardson
Jan 6, 2005·American Journal of Epidemiology·Hiroyasu IsoUNKNOWN JACC Study Group
Nov 18, 2005·Current Opinion in Critical Care·Martine LeblancRavindra Mehta
Oct 16, 2007·The Journal of Urology·Omer Toprak
May 5, 2010·Annals of Internal Medicine·Andrew D RuleMark D Stegall
Jun 22, 2010·Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular·Andréia Cristina PassaroniAna Cláudia Kochi
Jul 30, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Joana GuimarãesCarolina Garrett
Aug 31, 2010·Critical Care Medicine·Vincent DasGeorges Offenstadt
Aug 17, 2011·Nephron. Physiology·Andrew D RuleEmilio D Poggio
Sep 11, 2012·European Journal of Internal Medicine·Chia-Ter ChaoJenq-Wen Huang
May 25, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Giuseppe AndòGiuseppe Oreto
Oct 12, 2013·Handbook of Clinical Neurology·Pierre Pollak
Jan 15, 2014·Urologia·David Hernández HernándezDavid Castro-Diaz
Jan 22, 2014·Nature Reviews. Nephrology·Oleksa Rewa, Sean M Bagshaw
Feb 8, 2014·Journal of the American Society of Nephrology : JASN·Vin-Cent WuUNKNOWN NSARF Group
Feb 13, 2014·Journal of Cancer Research and Clinical Oncology·Chia-Ter ChaoUNKNOWN National Taiwan University Study Group on Acute Renal Failure
Mar 1, 2012·Kidney International Supplements
May 7, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Morgan E GramsUNKNOWN CKD Prognosis Consortium
May 16, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Matthew T JamesUNKNOWN CKD Prognosis Consortium
Oct 10, 2015·International Journal of Chronic Obstructive Pulmonary Disease·M F BarakatJ K Quint
Jun 24, 2016·American Journal of Respiratory and Critical Care Medicine·Faeq Husain-SyedClaudio Ronco
Aug 19, 2016·Diabetes, Obesity & Metabolism·Nicholas CarlsonGunnar Gislason
Feb 2, 2017·Journal of the American Society of Nephrology : JASN·Eoin D O'SullivanDavid A Ferenbach
Apr 13, 2017·International Urology and Nephrology·Pilar DomenechCarlos G Musso
Apr 13, 2017·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Rakesh MalhotraRavindra Mehta
May 6, 2017·PloS One·Che-Hsiung WuUNKNOWN National Taiwan University Study Group on Acute Renal Failure (NSARF)
Jun 18, 2017·Geriatrics & Gerontology International·Masanori YoshikawaHiroshi Kimura

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Citations

Feb 28, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C-T ChaoUNKNOWN COhort of GEriatric Nephrology in NTUH (COGENT) study group
May 10, 2018·BMC Research Notes·Ashraf O Oweis, Sameeha A Alshelleh
Oct 24, 2018·Journal of Clinical Medicine·Chia-Ter ChaoUNKNOWN COGENT Study Group (COhort of GEriatric Nephrology in NTUH)
Apr 17, 2020·Clinical Kidney Journal·Hilda O HounkpatinPaul J Roderick
Sep 29, 2018·Cardiovascular Diabetology·Chia-Ter ChaoUNKNOWN COhort of GEriatric Nephrology in NTUH (COGENT) study group
Jan 29, 2021·BioMed Research International·Si-Yang WangXiang-Mei Chen
Jul 2, 2021·Clinical and Experimental Nephrology·Gaetano AlfanoUNKNOWN Modena Covid-19 Working Group (MoCo19)

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