Age of onset in idiopathic (genetic) generalized epilepsies: clinical and EEG findings in various age groups

Seizure : the Journal of the British Epilepsy Association
Ali A Asadi-PooyaMichael R Sperling

Abstract

The prevalence and differences of idiopathic (genetic) generalized epilepsies (IGEs) with atypical age of onset compared to classical IGEs is a matter of debate. We tried to determine the clinical and EEG characteristics of IGEs in various age groups. All patients with a clinical diagnosis of IGE were recruited at the outpatient epilepsy clinic at Shiraz University of Medical Sciences from 2008 through 2011. We subdivided the patients into four different age groups: 4 years of age and under, 5-11 years, 12-17 years, and finally, 18 years and above, at the time of their epilepsy onset. Syndromic diagnosis, sex ratio, seizure types and EEG findings were compared. Statistical analyses were performed using Pearson Chi square test. 2190 patients with epilepsy were registered. 442 patients (20.2%) were diagnosed as having IGEs. Age of seizure onset was 12.4±6.9 years. The peak age of onset had a bimodal appearance. Sixty-seven patients (15.2%) were four years and under at the time of the onset of their disease, 112 persons (25.3%) were 5-11 years, 197 people (44.6%) were 12-17 years of age, and 66 patients (14.9%) had 18 years and above at the onset of their epilepsy. The sex ratio was significantly different between patients in grou...Continue Reading

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Citations

Nov 15, 2012·Journal of the Neurological Sciences·Ali A Asadi-PooyaMichael R Sperling
Aug 19, 2014·Neurobiology of Disease·Gilles van LuijtelaarMartin J Gallagher
May 31, 2014·Neurobiology of Disease·Ozlem AkmanAristea S Galanopoulou
Feb 5, 2013·Seizure : the Journal of the British Epilepsy Association·Ali A Asadi-PooyaAbbas Rahimi-Jaberi
Oct 30, 2012·Epilepsy & Behavior : E&B·Ali A Asadi-Pooya, Mehrdad Emami
Aug 28, 2012·Seizure : the Journal of the British Epilepsy Association·Ali A Asadi-Pooya, Mohaddese Sharifzade
Apr 30, 2013·Seizure : the Journal of the British Epilepsy Association·Muhammet BilgiHaldun Müderrisoğlu
Aug 11, 2020·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Shiva GanesanIngo Helbig
Dec 27, 2019·Neuroscience and Biobehavioral Reviews·Mujun SunSandy R Shultz
May 20, 2020·Revue neurologique·A NiloA Crespel

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