PMID: 15374037Sep 18, 2004Paper

Age-related and steroid induced changes in the histones of the quail liver

Archives of Gerontology and Geriatrics
G Mahendra, Madhu S Kanungo

Abstract

Histones were extracted from the liver of young, adult and old Japanese quails. Both linker and core histones were found to vary with age. An extra band, H3X, was found between H2A and H4. Its level is higher in young and old birds in comparison to that of the adult. H3X shows interesting changes under steroid induction. Its level is higher in progesterone administered young birds. In adult and old birds, it is higher in progesterone treated (P) and progesterone primed estradiol administered (P+E) birds, and lower in all estradiol (E) and estradiol primed progesterone administered (E+P) birds. The relative levels of H3X in the steroid administered birds also vary with age. Such changes may influence chromatin conformation and gene expression.

References

Jul 1, 1975·Biochemistry·B Sollner-Webb, G Felsenfeld
Sep 1, 1975·Journal of Theoretical Biology·M S Kanungo
Mar 15, 1985·Biochemical and Biophysical Research Communications·M M Chaturvedi, M S Kanungo
Nov 9, 1973·Nature·D L SmtihR A Smith
May 15, 1973·Biochemical and Biophysical Research Communications·D R Hewish, L A Burgoyne
Oct 27, 1970·Biochemistry·S C Elgin, J Bonner
Jul 1, 1994·Molecular Biology Reports·R N Mishra, M S Kanungo
Apr 16, 1998·Genes & Development·K Struhl
Mar 28, 1975·Science·M NollR D Kornberg

❮ Previous
Next ❯

Citations

May 31, 2014·Stem Cell Research·Liesbeth VossaertDieter Deforce
Oct 7, 2017·EMBO Reports·Jing ShenY Eugene Chin
Sep 25, 2020·Biogerontology·Pynskhem Bok Swer, Ramesh Sharma

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.