PMID: 9544893Apr 17, 1998Paper

Age-related changes in cardiovascular disease risk factors of hypercholesterolemic children

The Journal of Pediatrics
A M TershakovecB M Shannon

Abstract

To describe the age-related changes in cardiovascular disease risk factors in young, hypercholesterolemic (HC) children. Hypercholesterolemic (n = 227) and nonhypercholesterolemic (NHC) (n = 80) children between the ages of 4 and 10 years were identified. Height, weight, skin-fold and blood pressure measurements, and total cholesterol levels were measured. The HC group also had insulin levels evaluated. The groups were compared by analysis of variance. Simple Spearman correlations evaluated the associations between factors within each group. The HC and NHC groups had similar mean ages, heights, and weights, both contained 51% girls, and all were white subjects. Percent weight-for-height median, and biceps, triceps, suprailiac and subscapular skin-fold measurements were all larger for the HC group. A significant age interaction demonstrated that the HC group's larger suprailiac and sum of skin-fold measures were expressed in the 8.0- to 9.9-year-old children, but not the 4.0- to 5.9-year-olds. For both groups, systolic blood pressure was associated with the measures of adiposity. For the HC group, insulin levels were also associated with adiposity. These results suggest that: (1) children with HC have greater body fat, (2) the e...Continue Reading

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References

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Citations

Feb 20, 2004·Public Health Nutrition·I Darnton-HillW P T James
Nov 16, 2005·Obesity Research·L Beth DixonAndrew M Tershakovec
Apr 26, 2016·Advanced Biomedical Research·Saeed Kalantari
May 21, 2003·Journal of Human Hypertension·A E SchutteJ H de Ridder
Jun 19, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·V J TyrrellW S Cutfield
Sep 27, 2002·The American Journal of Clinical Nutrition·Andrew M TershakovecGerald S Berenson

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