Abstract
In the Childhood Brain Tumor Consortium database, the proportions of older children (> or = 11 yr) with pilocytic astrocytomas, fibrillary astrocytomas, and ependymomas significantly increased (P < 0.05) over the 50 years (1930-1979) of the study. The increased proportions of pilocytic astrocytomas occurred whether the tumors were located in the supratentorial or infratentorial compartments. The increases in fibrillary astrocytomas and ependymomas were found only within the supratentorial tumor location. Some histological features found in pilocytic astrocytomas (e.g., Rosenthal fibers, granular bodies, and very low cell density) were more likely to be found in older children. Other histological features were also more likely to be found in older children (e.g., parenchymal calcification, intertwined fascicles, intermediate and large-size nuclei, pleomorphic, elongated, or irregular nuclei, prominent nucleoli, multinucleated cells, thick hyaline blood vessels, hemosiderin, and parenchymal and perivascular lymphocytes). The probability of 5-year survival for young children with supratentorial ependymomas remained at approximately 0.4 in contrast to that for young children with infratentorial ependymomas, for whom it improved, bu...Continue Reading
References
Jan 1, 1978·Medical Hypotheses·A OhryR Rozin
Jan 22, 1979·Histochemistry·W Meyer
Apr 1, 1977·Journal of the National Cancer Institute·A FulchieroF H Gilles
Feb 1, 1976·Teratology·E B HookD W Smith
Jun 1, 1992·Journal of Neuro-oncology·F H GillesR A Sobel
Oct 17, 1990·Journal of the National Cancer Institute·N H GreigS I Rapoport
Sep 1, 1989·Journal of Neuro-oncology
Dec 1, 1987·Cancer Genetics and Cytogenetics·J A ReyJ Benitez
Aug 1, 1988·International Journal of Radiation Oncology, Biology, Physics·C R FreemanD Norris
Oct 1, 1985·Cancer·L B RorkeL E Becker
Jun 1, 1986·Cancer Genetics and Cytogenetics·S H BignerD D Bigner
Dec 1, 1988·Cancer·N L EbyP C Burger
Jan 1, 1988·Journal of Neuro-oncology
Mar 1, 1970·American Journal of Epidemiology·N W ChoiW H Gullen
Jun 22, 1970·Life Sciences. Pt. 2: Biochemistry, General and Molecular Biology·M F Collins
Nov 1, 1994·Journal of Neuropathology and Experimental Neurology·F H GillesE T Hedley-Whyte
Citations
Feb 15, 1997·Cancer·L B Rorke
Sep 26, 2006·Pathology Oncology Research : POR·Ajay MalikChitra Sarkar
Apr 1, 1997·Brain Pathology·R L Hamilton, I F Pollack
Feb 26, 2013·Acta Neuropathologica·Christian KoelscheDavid Capper
Jun 24, 2010·Neurocirugía·A Otero-RodríguezT Zamora-Martínez
Oct 9, 2007·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·V KiefferJ Grill
Apr 6, 2004·Pediatric Clinics of North America·Cormac O Maher, Corey Raffel
Mar 18, 2004·Neurosurgery Clinics of North America·Aaron S DumontMark E Shaffrey
Dec 19, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·L S LashfordUNKNOWN United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study
Apr 1, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Uri TaboriCynthia Hawkins
Apr 16, 2002·British Journal of Cancer·M CarterD W Ellison
Dec 5, 1998·Histopathology·T MatsumotoK Sato
Feb 4, 2005·Journal of Neuro-oncology·N K ForemanR Giller
Apr 3, 2009·Journal of Neuro-oncology·Monica BrownJennifer Dodge
Sep 10, 2014·Molecular Medicine Reports·Yoshinobu TakahashiJun-Ichi Kuratsu
Apr 19, 2000·Arquivos de neuro-psiquiatria·J S Reis FilhoL F Torres
Jul 1, 1996·Neurosurgery·E L SobelL S Adelman