Age-related changes in the medullary reticular epithelial cells of the pigeon bursa of Fabricius

The Anatomical Record
F Sanchez-RefustaJ A Vega

Abstract

The medulla of the avian bursal lymphoid follicles contains heterogeneous cell populations, including the so-called medullary reticular epithelial cells (REC). These cells may contribute to the bursal microenvironment for B-lymphocyte differentiation and maturation. The bursa of Fabricius undergoes well-characterized posthatching developmental changes, but the age-related changes of the medullary REC have not been studied. The present study approaches this topic by analyzing hallmarks of epithelial cells: the occurrence of cytokeratin-type intermediate filaments and of desmosomes and desmoplakins in pigeon medullary REC. The bursae of Fabricius of male king pigeons (Columba livia L.) Morini's strain were examined at different ages (from hatching to 120 days after hatching) by light microscopic immunohistochemistry for pan-cytokeratins and desmoplakins and by transmission electron microscopy. The area occupied by medullary cytokeratin-immunoreactive cells was evaluated with quantitative image analysis. At hatching, cytokeratin immunoreactivity was not detected in the bursal lymphoid follicles. During the posthatching growth period of the organ (7-75 days), there was a progressive and significant increase in the area occupied by ...Continue Reading

References

Jun 1, 1989·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·G I ViamontesG Goldstein
May 1, 1989·Differentiation; Research in Biological Diversity·T AchtstätterW W Franke
Nov 20, 1987·Science·J C Weill, C A Reynaud
May 1, 1995·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·E CiriacoJ A Vega
Nov 1, 1994·Immunology Today·M Dardenne, W Savino
Dec 1, 1994·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·E CiriacoJ A Vega

❮ Previous
Next ❯

Citations

Jun 15, 2010·Avian Pathology : Journal of the W.V.P.A·C CasteleynP Cornillie
Nov 25, 2003·Microscopy Research and Technique·Emilia CiriacoRosaria Laurà
Nov 25, 2003·Microscopy Research and Technique·Marta Torroba, Agustín G Zapata

❮ Previous
Next ❯

Related Concepts

Related Feeds

B cell Differentiation

Depending on the signal received through the B cell receptor and other receptors, B cells differentiate into follicular or marginal zone B cells. Here is the latest research pertaining to this differentiation process.

© 2021 Meta ULC. All rights reserved