PMID: 6392765Oct 31, 1984Paper

Age-related changes in the structure and function of chromatin: a review

Mechanisms of Ageing and Development
M K Thakur

Abstract

Due to rapid advancement in biochemical and biophysical techniques during the last decade, extensive studies have been undertaken to understand the structure and function of chromatin. Several interesting results have been reported regarding the changes in basic organization and function of chromatin during the life time of a eukaryotic cell. The data accumulated so far have been obtained with different organs and organisms and widely differing methods, and the conclusions drawn from them are sometimes contradictory. In this paper, therefore, the available data on the age-associated alterations in the composition, structure and function of chromatin have been discussed, and an attempt has been made to correlate the structural changes in chromatin with alteration in gene expression during aging.

References

Apr 20, 1977·Histochemistry·A MyśliwskiZ Kmieć
Sep 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·T Ono, R G Cutler
Jan 1, 1977·Annual Review of Biochemistry·R D Kornberg
Jan 12, 1978·Nature·G Felsenfeld
Feb 1, 1979·Mechanisms of Ageing and Development·R W HartS P Modak
May 1, 1979·Mechanisms of Ageing and Development·K NakanishiS Fujita
May 1, 1979·Experimental Cell Research·A T Garber, K Brasch
Sep 1, 1979·Journal of Gerontology·J GaubatzR Chalkley
May 1, 1979·The Biochemical Journal·V Zongza, A P Mathias
Dec 15, 1979·FEBS Letters·R S Piha, K H Valkonen
Dec 15, 1979·The Biochemical Journal·R Bolla, W D Denckla
Dec 21, 1977·Biochemical and Biophysical Research Communications·M S Kanungo, M K Thakur
Apr 14, 1978·Biochemical and Biophysical Research Communications·M K ThakurM S Kanungo
Jan 1, 1978·Biochemical Society Transactions·Z A Medvedev, M N Medvedeva
Aug 1, 1978·Journal of Cellular Physiology·S S AgarwalL A Loeb
Sep 29, 1978·Biochemical and Biophysical Research Communications·I R Brown
Dec 1, 1978·Mechanisms of Ageing and Development·T CastleA Richardson
Dec 1, 1978·Mechanisms of Ageing and Development·R T Dell'OrcoD L Simpson
Dec 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·J L ComptonP Chambon
Jan 20, 1977·Biochimica Et Biophysica Acta·C J ChetsangaC Johnson
Mar 1, 1977·Archives of Biochemistry and Biophysics·F Varricchio
Jun 15, 1976·Life Sciences·C J ChetsangaA Jacoboni
Jan 1, 1975·Journal of Gerontology·D B Carter, C B Chae
Jan 10, 1975·Nature·C J ChetsangaK Rushlow
Feb 1, 1975·Experimental Cell Research·G Stein
Jan 12, 1975·Biochemical and Biophysical Research Communications·S R GrimesJ L Irvin
Jul 1, 1975·Archives of Biochemistry and Biophysics·R Bolla, N Brot
Sep 1, 1975·Journal of Theoretical Biology·M S Kanungo

Citations

Dec 1, 1991·Aging : Clinical and Experimental Research·S Prasad, M K Thakur
Jul 1, 1986·Mechanisms of Ageing and Development·R T Dell'OrcoA Macieira-Coelho
Mar 1, 1986·Mechanisms of Ageing and Development·L Meheus, J R Vanfleteren
Jul 1, 1987·Mechanisms of Ageing and Development·K Anzai, S Goto
Mar 1, 1987·Mechanisms of Ageing and Development·M Hartwig, I J Körner
Nov 14, 1988·Mechanisms of Ageing and Development·M K Thakur
Dec 1, 1989·Mechanisms of Ageing and Development·A JaberaboansariK T Wheeler
Mar 31, 1990·Mechanisms of Ageing and Development·M K Thakur, S Prasad
Jan 1, 1993·Mechanisms of Ageing and Development·M K ThakurY Natori
Jan 31, 1995·Mechanisms of Ageing and Development·M KozurkováK Kropácová
Jan 1, 1995·Molecular Aspects of Medicine·S I Rattan
Jan 1, 1989·General Pharmacology·J PałygaJ Rafay
Jan 1, 1990·Experimental Gerontology·R S Sohal, R G Allen
Apr 1, 1997·Mechanisms of Ageing and Development·P Chaurasia, M K Thakur
Dec 31, 2003·Journal of Aging & Social Policy·P V Ramamurti
May 12, 2011·Current Gerontology and Geriatrics Research·Michel LebelVilhelm A Bohr
Jun 10, 2014·Ageing Research Reviews·Antero SalminenKai Kaarniranta
Oct 30, 2013·Journal of Cellular Biochemistry·Henrique F RodriguesAlberto S Moraes
Feb 1, 1991·Journal of Cellular Physiology·R T Dell'Orco, L E Anderson
Mar 31, 2010·Journal of Applied Measurement·Ulrich Müller, Willis F Overton

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