Abstract
We evaluated the effect of body growth and aging on the ratio of echocardiographic (Teichholz) stroke volume to pulse pressure (SV/PP ratio) in 373 normal-weight, normotensive children to adolescents (1 day to 17 years old; 166 girls, 87 nonwhite) and 393 normal adults (17 to 85 years old; 164 women, 112 nonwhite). Stroke volume increased with age in children (r = .64, P < .0001) and was stable in adults; pulse pressure decreased slightly with age in children (r = -.10, P = .06) and increased in adults (r = .29, P < .0001). As a consequence, SV/PP ratio increased with age in children (r = .51, P < .0001) and decreased in adults (r = -.18, P = .0004). To control for changes in body size that influence the size of the arterial tree, we used ANCOVA to adjust SV/PP for body size. Body size-adjusted SV/PP ratio was no longer related to age in children, whereas the negative relation with aging in adults remained statistically significant (r = -.19, P < .0002). Heart rate was negatively related to SV/PP ratio in both children and adolescents and adults, but this relation did not influence the relation with age. In multivariate analysis, high SV/PP ratio was predicted by greater height (P < .002) and weight (P < .04) and nonwhite race ...Continue Reading
References
Jan 1, 1976·The American Journal of Cardiology·L E TeichholzR Gorlin
Dec 1, 1990·European Heart Journal·D C WallersonR B Devereux
Nov 1, 1990·European Heart Journal·M O'Rourke
May 1, 1990·Clinical Cardiology·R B Hickler
Sep 1, 1989·The American Journal of Cardiology·M J RomanJ O'Loughlin
Jun 1, 1987·Annals of Internal Medicine·M J RomanJ S Borer
Feb 1, 1973·Bulletin of Mathematical Biology·J G Defares, M E Wise
Apr 1, 1995·The American Journal of Physiology·N StergiopulosN Westerhof
Jan 1, 1995·Ultrasound in Medicine & Biology·F HansenT Länne
May 1, 1994·Journal of the American College of Cardiology·G de SimoneJ H Laragh
Dec 1, 1993·The Journal of Pediatrics·B RosnerS R Daniels
Feb 1, 1994·The American Journal of Clinical Nutrition·J H Himes, W H Dietz
Sep 1, 1995·Journal of Hypertension·P S SabaR B Devereux
Citations
Oct 12, 1999·Clinical Physiology·L LindM Edner
Mar 20, 2001·American Journal of Physiology. Gastrointestinal and Liver Physiology·J H HenriksenS Møller
Dec 4, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Francesco SalernoLarry Burdick
Apr 16, 2004·Journal of Human Hypertension·M H OlsenR B Devereux
Mar 31, 2009·Journal of Hypertension·Giovanni de SimoneOreste de Divitiis
Jun 1, 2012·Annals of Biomedical Engineering·Orestis VardoulisNikolaos Stergiopulos
May 21, 2014·American Journal of Hypertension·Melissa C CaugheyAlan L Hinderliter
Sep 1, 2007·Expert Review of Endocrinology & Metabolism·Wilmer W NicholsRandy W Braith
Feb 24, 2001·Journal of Hypertension·J N BellaR B Devereux
Feb 24, 2001·Journal of Hypertension·G de SimoneR B Devereux
Oct 11, 2001·Journal of Hypertension·G de SimoneJ M Gardin
Oct 3, 2002·Journal of Hypertension·Elke WühlUNKNOWN German Working Group on Pediatric Hypertension
Mar 18, 2003·Journal of Hypertension·Michael F O'Rourke, Chris S Hayward
Apr 21, 2004·Journal of Hypertension·Lars LindJohan Sundström
Dec 20, 2019·Journal of Applied Physiology·A MulchroneN C Chesler
Jul 27, 1999·Journal of Hypertension·G de SimoneM J Roman
Jun 21, 2001·The American Journal of Geriatric Cardiology·Michael D. VanAuker
Feb 1, 2002·Journal of Hypertension·Giovanni de SimoneRichard B Devereux
Aug 21, 2008·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Lin ZhouXirong Liu
Feb 25, 2011·Journal of Hypertension·Pascal RossiAnna A Ahimastos
Nov 18, 2011·Nutrition Journal·Joan A Vaccaro, Fatma G Huffman
Mar 15, 2012·Scandinavian Journal of Gastroenterology·Jens H HenriksenFlemming Bendtsen
Dec 13, 2012·Journal of Clinical Ultrasound : JCU·Kara L MarlattDonald R Dengel
Apr 28, 2017·Clinical and Experimental Hypertension : CHE·Atsushi NakagomiYoshio Kobayashi
Aug 22, 2001·American Journal of Physiology. Heart and Circulatory Physiology·D BaldassarreC R Sirtori
Nov 16, 2010·Cardiovascular Ultrasound·Tonino BombardiniEugenio Picano
Jul 16, 2014·Hypertension·Alyssa A TorjesenGary F Mitchell
Apr 19, 2017·Clinical Hypertension·Bae Keun KimJinho Shin
Jan 18, 2021·The International Journal of Cardiovascular Imaging·Nicholas W S ChewKian Keong Poh
Jun 16, 2005·Kidney International·Christopher T ChanJohn S Floras
May 23, 2006·Metabolism: Clinical and Experimental·Hannu PäiväReijo Laaksonen