Age-related decline in cold tolerance can be retarded by brain stimulation

Physiology & Behavior
M I TalanJ R Whitaker

Abstract

The sharp decline in capacity of old C57BL/6J male mice to maintain body temperature during 3-hr cold exposure can be delayed and even partly restored after 15, 30-min, daily sessions of hypothalamic self-stimulation. In control experiments it was demonstrated that electrical stimulation of "rewarding" areas of hypothalamus itself is sufficient for improvement of the age-related deterioration of thermoregulatory ability.

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Citations

Jan 1, 1988·Physiology & Behavior·M I Talan, B T Engel
Nov 14, 1986·Mechanisms of Ageing and Development·M I Talan, D K Ingram
Oct 1, 1988·Mechanisms of Ageing and Development·L PénzesO Regius
Oct 1, 1985·Archives of Gerontology and Geriatrics·M I Talan, D K Ingram
Nov 11, 2011·The Cochrane Database of Systematic Reviews·Tracey E HoweClaire Ballinger
Aug 16, 2014·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Alice J S FoxScott A Rodeo
Sep 10, 2014·International Journal of Environmental Research and Public Health·Francisco B TeixeiraRafael R Lima
Dec 29, 2019·Physiological Reports·Charline DambrevilleLaurent Bouyer
Apr 30, 1998·Physiological Reviews·M Florez-Duquet, R B McDonald

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