Age-Related Differences in Presentation, Treatment, and Outcome of Patients With Atrial Fibrillation in Europe: The EORP-AF General Pilot Registry (EURObservational Research Programme-Atrial Fibrillation)

JACC. Clinical Electrophysiology
Stefano FumagalliEORP-AF Investigators

Abstract

This study sought to compare age-related differences in presentation, treatment, and outcome of atrial fibrillation (AF) in a wide cohort of European subjects. AF is the most common sustained arrhythmia in the elderly. We evaluated all patients enrolled in the EORP-AF (EURObservational Research Programme-Atrial Fibrillation) General Pilot Registry in 70 centers of 9 European countries. Among 3,119 subjects, 1,051 (33.7%) were age ≥75 years. Permanent AF was significantly more common in the elderly, who had a higher prevalence of hypertension, valvular diseases, chronic heart failure, coronary artery disease, renal failure, chronic obstructive pulmonary disease, and prior hemorrhagic event or a transient ischemic attack. Common diagnostic tests were underused in older subjects. Despite their higher stroke risk, the use of oral anticoagulants was significantly lower in the elderly (76.7% vs. 82.8%; p = 0.0012), whereas aspirin and clopidogrel alone or in combination were more often prescribed. Rate control was the management of choice in the older group, with electrical cardioversion and catheter ablation performed less frequently than in the younger age group. Antiarrhythmic drugs were significantly less prescribed in the elderl...Continue Reading

Associated Clinical Trials

References

Nov 1, 1995·Age and Ageing·J G Evans
Nov 24, 1999·BMJ : British Medical Journal·A Bowling
Nov 19, 2002·JAMA : the Journal of the American Medical Association·Carl van WalravenBeppie Hellemons
Mar 25, 2005·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Michael J LimRajendra H Mehta
Oct 6, 2005·European Heart Journal·Robby NieuwlaatUNKNOWN European Heart Survey Investigators
Mar 11, 2006·European Heart Journal·Jan HeeringaJacqueline C M Witteman
Sep 12, 2006·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Karin S CoynePeter Zimetbaum
Mar 6, 2007·Journal of the American College of Cardiology·Yoko MiyasakaTeresa S M Tsang
Sep 2, 2009·Annals of Internal Medicine·Daniel E SingerAlan S Go
Sep 26, 2009·Journal of the American College of Cardiology·Jonathan P PicciniUNKNOWN Get With The Guidelines Steering Committee and Hospitals
Nov 19, 2009·Aging Clinical and Experimental Research·Stefano FumagalliUNKNOWN GIFA Study Research Group
Jan 9, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Fernando ArribasXavier Badia
Feb 24, 2011·International Journal of Cardiology·Raymond CutroPaul J Hauptman
Sep 17, 2011·Circulation. Heart Failure·Alanna M ChamberlainVéronique L Roger
Aug 14, 2012·International Journal of Cardiology·Giuseppe Di PasqualeUNKNOWN ATA-AF Investigators
Aug 28, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·A John CammUNKNOWN Document Reviewers
Feb 2, 2013·The American Journal of Medicine·Prakash C Deedwania
May 10, 2013·Circulation Journal : Official Journal of the Japanese Circulation Society·Gregory Y H Lip, Deirdre A Lane
Jun 7, 2013·Neurology·Evan L ThackerSusan R Heckbert
Jun 22, 2013·The American Journal of Medicine·Paul L HessGregg C Fonarow
Sep 24, 2013·The American Journal of Medicine·Nasir ShariffAli Ahmed
Dec 19, 2013·Circulation·Sumeet S ChughChristopher J L Murray
Dec 20, 2013·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Gregory Y H LipAldo P Maggioni
May 3, 2014·Journal of the American Geriatrics Society·Partha SardarGregory Y H Lip

❮ Previous
Next ❯

Citations

Apr 25, 2020·Journal of Comparative Effectiveness Research·Carmen Suárez FernándezFrancesc Formiga
Aug 24, 2019·Frontiers in Medicine·Zafraan ZatharGregory Y H Lip
May 14, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Stefano FumagalliNikolaos Dagres
Apr 12, 2021·Revista Española De Cardiología·Sergio Raposeiras-RoubínAndrés Íñiguez Romo
Jan 14, 2022·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Yutao GuoGregory Y H Lip

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Related Papers

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Giuseppe BorianiGregory Y H Lip
European Heart Journal. Cardiovascular Pharmacotherapy
Stefano FumagalliEORP-AF General Pilot Registry Investigators
© 2022 Meta ULC. All rights reserved