PMID: 15219042Jun 29, 2004Paper

Age-related hearing loss and its association with reactive oxygen species and mitochondrial DNA damage

Acta Oto-laryngologica. Supplementum
Michael D SeidmanWayne S Quirk

Abstract

Age-related hearing loss, known as presbyacusis, is characterized by the progressive deterioration of auditory sensitivity associated with the aging process and is the leading cause of adult auditory deficiency in the USA. Presbyacusis is described as a progressive, bilateral, high-frequency hearing loss that is manifested on audiometric assessment by a moderately sloping pure tone audiogram. Approximately 23% of the population between 65 and 75 years of age, and 40% of the population older than 75 years of age are affected by this condition. It was estimated in 1980 that 11% of the population was 76 years or older and this number is expected to almost double by the year 2030. When one considers that the population over 65 years of age is experiencing the most accelerated development of hearing loss, the potential socioeconomic ramifications are staggering. Curiously, the frequency of presbyacusis varies across different societies. This discrepancy has been attributed to many factors including genetics, diet, socioeconomic factors, and environmental variables. The purpose of this article is to review the various molecular mechanisms underlying presbyacusis and to offer insights into potential methods of mitigating the effects o...Continue Reading

Citations

Mar 15, 2014·The Journal of Nutrition, Health & Aging·B GopinathP Mitchell
Aug 17, 2010·The Journal of the Acoustical Society of America·James J Finneran, Carolyn E Schlundt
Jun 9, 2014·Archives of Environmental Contamination and Toxicology·Zhongkun DuYingying Guo
May 14, 2010·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Qi Huang, Jianguo Tang
Oct 16, 2013·The American Journal of Medicine·Sharon G CurhanGary C Curhan
Dec 21, 2010·Hearing Research·Z MassidaO Deguine
Dec 18, 2009·American Journal of Otolaryngology·Gerald M HaaseSuzanne E Wyatt
Nov 23, 2007·Neurobiology of Aging·Vânia Belintani PiattoJosé Victor Maniglia
Apr 10, 2009·The Laryngoscope·Adam MarkaryanRaul Hinojosa
Aug 19, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Michelangelo MancusoGabriele Siciliano
Jun 1, 2011·International Journal of Dermatology·Hayriye KarabulutRıza Murat Karaşen
Jan 31, 2013·Hearing Research·Erik C Böttger, Jochen Schacht
Jun 15, 2011·Hearing Research·Brianna K Crawley, Elizabeth M Keithley
Jul 18, 2015·Journal of Audiology & Otology·Ji Young Lee
May 17, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Kourosh Parham
Feb 6, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michael D SeidmanRobert T Standring
May 5, 2016·Journal of Audiology & Otology·Sema KoçNurten Aksoy
Aug 7, 2013·Rejuvenation Research·Hong Miao RenWei Liu
Jul 31, 2018·American Journal of Epidemiology·Jingjing ZhuXiao-Ou Shu
Sep 8, 2007·Current Opinion in Otolaryngology & Head and Neck Surgery·Ilaaf DarratMichael D Seidman
Nov 24, 2005·Acta Oto-laryngologica·Masaya Takumida, Matti Anniko
Oct 20, 2006·Acta Oto-laryngologica·Julián NevadoRafael Ramírez-Camacho
Aug 30, 2006·International Journal of Audiology·Adrian Fuente, Bradley McPherson
Jul 9, 2008·Acta Oto-laryngologica·Masaya Takumida, Matti Anniko
Oct 4, 2019·Vestnik otorinolaringologii·N L KunelskayaY V Luchsheva
Sep 17, 2011·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Kuzma StrelnikovOlivier Deguine
May 6, 2010·Acta Oto-laryngologica·Julián NevadoRafael Ramírez-Camacho
Nov 21, 2009·International Journal of Audiology·Chun-Ching Wu, Yi-Ho Young
Nov 5, 2014·Aging Clinical and Experimental Research·Taye Jemilat Lasisi, Akeem Olawale Lasisi
Nov 20, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Elham Tavanai, Ghassem Mohammadkhani
Feb 3, 2018·Aging and Disease·Weiming HuJianguo Tang
Nov 23, 2018·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Mustafa Celik, İsmail Koyuncu
Mar 25, 2019·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Purnami Nyilo, Manyakori Serafika Permoni Putri
Nov 22, 2019·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Elham TavanaiShohreh Jalaie
Nov 25, 2020·Proceedings of the National Academy of Sciences of the United States of America·Sophie BoucherChristine Petit
Jun 23, 2018·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·M ShimojiD A Depireux
May 5, 2021·The Journal of the Acoustical Society of America·Bernhard RossAnnette Schumann
Jul 3, 2021·International Journal of Environmental Research and Public Health·Jessie Chao-Yun ChiHua Ting

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Speech, Language, and Hearing Research : JSLHR
Kathryn H ArehartChristi Wise Miller
Current Opinion in Otolaryngology & Head and Neck Surgery
Michael Anne Gratton, Ana Elena Vázquez
Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Naoki OishiKaoru Ogawa
© 2022 Meta ULC. All rights reserved