Age-related heterogeneity in dental caries and associated risk factors in individuals with cystic fibrosis ages 6-20 years: A pilot study

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Donald L ChiJoAnna Scott

Abstract

The literature conflicts regarding dental caries risk in cystic fibrosis (CF) relative to controls. Prospective, observational study of age-related heterogeneity in caries rates and potential risk factors in individuals with CF ages 6-20 at a single clinic in Washington state (N=85). Caries rates for enrolled CF participants and historical controls from NHANES were compared using cubic spline regression models. Generalized linear regression models identified correlates of age and caries in CF. Children ages 6-9 with CF had significantly lower caries than controls (Holm's P<0.05). There was no difference for ages 10-20 by CF status (Holm's P>0.05). Various biological/intraoral, medical, and behavioral factors were associated with caries and age in CF. Younger children with CF may be protected from caries, but there is apparent loss of protection in early adolescence associated with multiple risk factors. Additional studies are needed to confirm these findings.

Citations

Apr 20, 2020·International Journal of Paediatric Dentistry·Jeffrey N LeeDonald L Chi
May 28, 2019·Pediatric Pulmonology·Adrienne P Savant, Susanna A McColley
Feb 27, 2020·Journal of Periodontology·Zeynep Pinar Keles YucelNagihan Bostanci
Mar 23, 2021·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Alaa A AlkhateebDonald L Chi

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