Age-related macular degeneration in Portugal: prevalence and risk factors in a coastal and an inland town. The Coimbra Eye Study - Report 2

Acta Ophthalmologica
Maria da Luz CachuloRufino Silva

Abstract

To determine the age- and sex-specific prevalence of early and late age-related macular degeneration (AMD) in two Portuguese population-based samples and to identify its risk factors. A population of 6023 adults aged ≥55 years was recruited from two Portuguese primary healthcare units in the central region of Portugal - one from a coastal (n = 3000) and another from an inland town (n = 3023). Cross-sectional population-based study. Participants were enrolled in the two locations between August 2009 and October 2013. Responders underwent standardized interviews and ophthalmologic examination, including digital fundus imaging. All fundus photographs were graded according to an International Classification and Grading System. The main outcome measures consisted of age- and sex-adjusted prevalence of early and late AMD. Potential epidemiologic risk factors were also evaluated using logistic regression analysis. Of the 6023 subjects enrolled, 5996 had gradable fundus images and were included in the analysis. The crude prevalence of early and late AMD was 6.99 and 0.67%, respectively, for the coastal town and 15.39 and 1.29% for the inland town. Age- and sex-adjusted prevalence of any AMD for the Portuguese population was 12.48% (95%...Continue Reading

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Citations

Jul 10, 2018·BioMed Research International·Joana ProvidênciaRufino Silva
May 5, 2020·Ophthalmic Epidemiology·Pedro Lima RamosAntonio Filipe Macedo
Feb 6, 2017·Oxidative Medicine and Cellular Longevity·Ângela Carneiro, José Paulo Andrade
Mar 20, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Cláudia FarinhaRufino Silva
Mar 2, 2019·Ophthalmic Research·Cláudia Virgínia Louro FarinhaRufino Silva

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