Get paper from

journal cover

Age-related sperm DNA methylation changes are transmitted to offspring and associated with abnormal behavior and dysregulated gene expression

Molecular Psychiatry

Aug 1, 2015

Maria H MilekicJay A Gingrich

Get paper from

Abstract

Advanced paternal age (APA) has been shown to be a significant risk factor in the offspring for neurodevelopmental psychiatric disorders, such as schizophrenia and autism spectrum disorders. During aging, de novo mutations accumulate in the male germline and are frequently transmitted t...read more

8
1
1
117
Paper Details
References
    • References49
    • Citations21
    • References49
    • Citations21
  • Age-related sperm DNA methylation changes are transmitted to offspring and associated with abnormal behavior and dysregulated gene expression

    Molecular Psychiatry

    Aug 1, 2015

    Maria H MilekicJay A Gingrich

    PMID: 25092244

    DOI: 10.1038/mp.2014.84

    Abstract

    Advanced paternal age (APA) has been shown to be a significant risk factor in the offspring for neurodevelopmental psychiatric disorders, such as schizophrenia and autism spectrum disorders. During aging, de novo mutations accumulate in the male germline and are frequently transmitted t...read more

    8
    1
    1
    117

    Related Papers

    Paper Details
    References
    • References49
    • Citations21
    • References49
    • Citations21
  • Get paper from

    © 2019 Meta ULC. All rights reserved.

    Hi! We use cookies on this site for analytics purposes. Visit our cookie policy to learn more. By continuing to use our services or closing this banner, you consent to our use of cookies.

    /papers/age-related-sperm-dna-methylation-changes-are/25092244