Ageing and infertility: an overview

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Juan Balasch


In many modern societies, the proportion of women who delay childbearing beyond the age of 35 years has increased greatly in recent decades. They are falsely reassured by popular beliefs that advances in new reproductive technologies can compensate for the age-realted decline in fertility, but science cannot beat the biological clock. Age is the single most important determinant of male and female fertility, either natural or treated. The consequences of advancing maternal age are not only for the risk of natural and assisted conception, but also for the outcome of pregnancy. Female fertility has a 'best-before date' of 35, and for men, it is probably before age 45-50.


Mar 1, 1992·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·J BalaschJ A Vanrell
Oct 1, 1991·Human Reproduction·J CosteH Fernandez
Sep 26, 1986·Science·J MenkenU Larsen
Oct 12, 1995·The New England Journal of Medicine·R C FrettsM B Goldman
Jan 23, 1999·Obstetrics and Gynecology·W M GilbertB Danielsen
Jun 23, 2000·BMJ : British Medical Journal·A M Nybo AndersenM Melbye
Sep 26, 2000·Fertility and Sterility·R Ron-ElS Friedler
May 29, 2002·Current Opinion in Obstetrics & Gynecology·Neal G Mahutte, Aydin Arici
Feb 1, 2003·Journal of the American Geriatrics Society·UNKNOWN American Geriatrics Society Ethics Committee
Aug 12, 2003·Fertility and Sterility·Michael R Soules, UNKNOWN American Society for Reproductive Medicine
May 12, 2004·Fertility and Sterility·UNKNOWN Society for Assisted Reproductive Technology, UNKNOWN American Society for Reproductive Medicine
Jun 12, 2004·Human Reproduction Update·UNKNOWN ESHRE Capri Workshop Group
Jun 12, 2004·Human Reproduction Update·Bianca Kühnert, Eberhard Nieschlag
Nov 5, 2004·The New England Journal of Medicine·Linda J Heffner
Mar 31, 2005·The Journal of Clinical Endocrinology and Metabolism·Sérgio Reis SoaresAntonio Pellicer
Apr 16, 2005·Human Reproduction Update·D T BairdUNKNOWN ESHRE Capri Workshop Group
May 3, 2005·Obstetrics and Gynecology·Jane Cleary-GoldmanUNKNOWN FASTER Consortium
Sep 30, 2005·Cytogenetic and Genome Research·F PellestorS Hamamah
Oct 20, 2006·Best Practice & Research. Clinical Obstetrics & Gynaecology·Ernest Hung Yu Ng, Pak Chung Ho
Oct 2, 2007·Fertility and Sterility·Abha MaheshwariSiladitya Bhattacharya
Sep 4, 2008·Reproductive Biomedicine Online·Stéphanie BellocYves Ménézo
May 28, 2009·Nature Genetics·Patricia Hartge

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Sep 24, 2013·Best Practice & Research. Clinical Endocrinology & Metabolism·Michael Zitzmann
Dec 14, 2011·Asian Journal of Andrology·Zofnat Wiener-MegnaziMartha Dirnfeld
Jan 11, 2016·Journal of Assisted Reproduction and Genetics·Mai OginoHiroaki Shibahara
Dec 31, 2015·International Journal of Technology Assessment in Health Care·Devidas MenonTania Stafinski
Aug 31, 2012·Science China. Life Sciences·JunHao YanZi-Jiang Chen
Dec 14, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Anne Britt Vika NilsenErica Schytt
Jun 12, 2013·Journal of Clinical Nursing·Stefania MannariniGuido Ambrosini
Nov 18, 2015·The American Journal of Bioethics : AJOB·Marie-Eve Lemoine, Vardit Ravitsky
Apr 14, 2016·Fertility and Sterility·Signe HolstAllan Jensen
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Jul 2, 2016·Human Reproduction·J DattaK Wellings
Jun 4, 2013·Evolutionary Psychology : an International Journal of Evolutionary Approaches to Psychology and Behavior·Susanne RöderBenedict C Jones
Sep 14, 2018·The Journal of Psychology·Vera SkvirskyEran Horowitz
Jun 22, 2019·Clinical and Experimental Reproductive Medicine·Azita FaramarziEsmat Mangoli
Oct 4, 2017·Oncotarget·Te-Sha TsaiJustin C John
Apr 22, 2015·Reproduction, Fertility, and Development·Neha Garg, David A Sinclair
Jul 2, 2011·Reproductive Medicine and Biology·Toshifumi TakahashiHirohisa Kurachi
Nov 26, 2016·Stress and Health : Journal of the International Society for the Investigation of Stress·Shirley Ben ShlomoEran Horowitz
Feb 9, 2021·Journal of Assisted Reproduction and Genetics·Adão Francisco LucasYapo G Aboua
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