Dec 23, 2015

Agent-based modeling of cancer stem cell driven solid tumor growth

BioRxiv : the Preprint Server for Biology
Jan PoleszczukHeiko Enderling

Abstract

Computational modeling of tumor growth has become an invaluable tool to simulate complex cell-cell interactions and emerging population-level dynamics. Agent-based models are commonly used to describe the behavior and interaction of individual cells in different environments. Behavioral rules can be informed and calibrated by in vitro assays, and emerging population-level dynamics may be validated with both in vitro and in vivo experiments. Here, we describe the design and implementation of a lattice-based agent-based model of cancer stem cell driven tumor growth.

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Mentioned in this Paper

In Vivo
Environment
Cell Communication
Tumor Growth
Cancer Stem Cells
In Vitro [Publication Type]
Research Study

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