PMID: 2494149Mar 1, 1989Paper

Aggravation of diabetic nephropathy by lithium: a case report and review of the literature

The Journal of Clinical Psychiatry
B R PawelA W Crosson

Abstract

A manic-depressive diabetic man receiving lithium carbonate therapy had massive proteinuria, which dramatically improved after the withdrawal of lithium. The authors discuss previous cases of lithium-induced nephrotic syndrome in nondiabetics and draw attention to the possibility that lithium therapy aggravates protein excretion in diabetic patients.

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